KCTD12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051260Biological processprotein homooligomerization
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0042995Cellular componentcell projection
GO_0045211Cellular componentpostsynaptic membrane
GO_0043235Cellular componentreceptor complex
GO_0042734Cellular componentpresynaptic membrane
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameKCTD12
Protein namePotassium channel tetramerisation domain containing 12 (Testicular tissue protein Li 100)
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)
SynonymshCG_1646360
KIAA1778
C13orf2
PFET1
DescriptionFUNCTION: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). .

AccessionsENST00000377474.4
Q96CX2
A0A140VJM4