ITIH4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ITIH4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ITIH4 at tissue level.

III. Associated gene sets

GO_0030212Biological processhyaluronan metabolic process
GO_0006953Biological processacute-phase response
GO_0034097Biological processresponse to cytokine
GO_0072562Cellular componentblood microparticle
GO_0070062Cellular componentextracellular exosome
GO_0031089Cellular componentplatelet dense granule lumen
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005886Cellular componentplasma membrane
GO_0004866Molecular functionendopeptidase inhibitor activity
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameITIH4
Protein nameInter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]
Inter-alpha-trypsin inhibitor heavy chain 4
Inter-alpha (Globulin) inhibitor H4 (Plasma Kallikrein-sensitive glycoprotein)
ITIH4 protein (Inter-alpha-trypsin inhibitor heavy chain 4)
SynonymsPK120
ITIHL1
IHRP
PRO1851
DescriptionFUNCTION: Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. .

AccessionsH7C0L5
ENST00000485816.5
ENST00000406595.5 [Q14624-3]
ENST00000441637.2
Q14624
B7ZKJ8
B2RMS9
ENST00000266041.9 [Q14624-1]