Insufficient scRNA-seq data for expression of ITIH4 at single-cell level.
Insufficient scRNA-seq data for expression of ITIH4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 213432.15 | 226 / 226 | 93% | 8.18 | 377 / 406 |
pancreas | 100% | 6370.20 | 328 / 328 | 8% | 0.18 | 15 / 178 |
adrenal gland | 100% | 3967.73 | 257 / 258 | 1% | 0.03 | 3 / 230 |
bladder | 100% | 1710.48 | 21 / 21 | 1% | 0.02 | 3 / 504 |
spleen | 100% | 2815.83 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 7969.40 | 1332 / 1335 | 0% | 0 | 0 / 0 |
thymus | 99% | 1871.81 | 647 / 653 | 0% | 0.00 | 1 / 605 |
lung | 97% | 1723.89 | 563 / 578 | 1% | 0.02 | 16 / 1155 |
prostate | 98% | 1536.78 | 239 / 245 | 0% | 0 | 0 / 502 |
muscle | 97% | 6438.46 | 780 / 803 | 0% | 0 | 0 / 0 |
uterus | 93% | 1100.13 | 158 / 170 | 3% | 0.03 | 12 / 459 |
kidney | 90% | 1334.18 | 80 / 89 | 4% | 0.07 | 32 / 901 |
stomach | 87% | 925.83 | 314 / 359 | 0% | 0 | 0 / 286 |
breast | 85% | 934.04 | 391 / 459 | 1% | 0.01 | 7 / 1118 |
intestine | 84% | 1033.71 | 816 / 966 | 1% | 0.01 | 3 / 527 |
adipose | 84% | 1050.47 | 1008 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 77% | 1226.48 | 716 / 929 | 0% | 0 | 0 / 0 |
esophagus | 70% | 818.88 | 1013 / 1445 | 0% | 0 | 0 / 183 |
ovary | 69% | 663.77 | 125 / 180 | 0% | 0.01 | 2 / 430 |
brain | 54% | 440.23 | 1430 / 2642 | 0% | 0 | 0 / 705 |
skin | 51% | 460.63 | 916 / 1809 | 0% | 0 | 0 / 472 |
heart | 47% | 413.14 | 407 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030212 | Biological process | hyaluronan metabolic process |
GO_0006953 | Biological process | acute-phase response |
GO_0034097 | Biological process | response to cytokine |
GO_0072562 | Cellular component | blood microparticle |
GO_0070062 | Cellular component | extracellular exosome |
GO_0031089 | Cellular component | platelet dense granule lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0005886 | Cellular component | plasma membrane |
GO_0004866 | Molecular function | endopeptidase inhibitor activity |
GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ITIH4 |
Protein name | Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4] Inter-alpha-trypsin inhibitor heavy chain 4 Inter-alpha (Globulin) inhibitor H4 (Plasma Kallikrein-sensitive glycoprotein) ITIH4 protein (Inter-alpha-trypsin inhibitor heavy chain 4) |
Synonyms | PK120 ITIHL1 IHRP PRO1851 |
Description | FUNCTION: Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration. . |
Accessions | H7C0L5 ENST00000485816.5 ENST00000406595.5 [Q14624-3] ENST00000441637.2 Q14624 B7ZKJ8 B2RMS9 ENST00000266041.9 [Q14624-1] |