INPP5B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070613Biological processregulation of protein processing
GO_0007283Biological processspermatogenesis
GO_0001701Biological processin utero embryonic development
GO_0007165Biological processsignal transduction
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_0043647Biological processinositol phosphate metabolic process
GO_0030317Biological processflagellated sperm motility
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0031901Cellular componentearly endosome membrane
GO_0005794Cellular componentGolgi apparatus
GO_0005829Cellular componentcytosol
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0030670Cellular componentphagocytic vesicle membrane
GO_0052658Molecular functioninositol-1,4,5-trisphosphate 5-phosphatase activity
GO_0004439Molecular functionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO_0052659Molecular functioninositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameINPP5B
Protein nameType II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)
Inositol polyphosphate-5-phosphatase B
SynonymsOCRL2
DescriptionFUNCTION: Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events. .

AccessionsENST00000373026.5 [P32019-1]
ENST00000373021.1
P32019
ENST00000373024.8 [P32019-2]
ENST00000373027.5 [P32019-3]
B1ARF3