IGHMBP2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IGHMBP2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IGHMBP2 at tissue level.

III. Associated gene sets

GO_0032508Biological processDNA duplex unwinding
GO_0010501Biological processRNA secondary structure unwinding
GO_0016020Cellular componentmembrane
GO_0005654Cellular componentnucleoplasm
GO_0016604Cellular componentnuclear body
GO_0030426Cellular componentgrowth cone
GO_0005737Cellular componentcytoplasm
GO_0030424Cellular componentaxon
GO_1990904Cellular componentribonucleoprotein complex
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0003677Molecular functionDNA binding
GO_0003727Molecular functionsingle-stranded RNA binding
GO_0003697Molecular functionsingle-stranded DNA binding
GO_0043022Molecular functionribosome binding
GO_0036121Molecular functiondouble-stranded DNA helicase activity
GO_0042802Molecular functionidentical protein binding
GO_0008186Molecular functionATP-dependent activity, acting on RNA
GO_0032574Molecular function5'-3' RNA helicase activity
GO_0003678Molecular functionDNA helicase activity
GO_0008270Molecular functionzinc ion binding
GO_0043139Molecular function5'-3' DNA helicase activity
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding
GO_0008094Molecular functionATP-dependent activity, acting on DNA
GO_0000049Molecular functiontRNA binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameIGHMBP2
Protein nameDNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2)
Immunoglobulin mu DNA binding protein 2
DNA helicase (EC 3.6.4.12)
SynonymsSMUBP2
SMBP2
DescriptionFUNCTION: 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction . Specific to 5'-phosphorylated single-stranded guanine-rich sequences . May play a role in RNA metabolism, ribosome biogenesis or initiation of translation . May play a role in regulation of transcription (By similarity). Interacts with tRNA-Tyr . .

AccessionsENST00000676228.1
A0A6Q8PHR8
A0A6Q8PFN4
A0A6Q8PGF6
ENST00000675615.1
A0A6Q8PFP3
A0A6Q8PFZ7
ENST00000675683.1
A0A6Q8PHG1
ENST00000674675.1
ENST00000675464.1
H3BRR1
A0A6Q8PF01
A0A6Q8PGC0
ENST00000675684.1
A0A6Q8PGT6
P38935
ENST00000674955.1
ENST00000675119.1
ENST00000675118.1
ENST00000675305.1
F5GX64
A0A6Q8PEZ5
ENST00000675873.1
ENST00000545146.1
A0A6Q8PFK9
ENST00000675469.1
ENST00000674745.1
A0A6Q8PGQ2
ENST00000675916.1
A0A6Q8PF41
ENST00000674878.1
A0A6Q8PF00
ENST00000676182.1
ENST00000255078.8
A0A6Q8PGQ6
ENST00000674583.1
ENST00000674597.1
A0A6Q8PHH4
A0A6Q8PGX2
ENST00000539224.2