IFT81 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008589Biological processregulation of smoothened signaling pathway
GO_0060271Biological processcilium assembly
GO_0007283Biological processspermatogenesis
GO_0120316Biological processsperm flagellum assembly
GO_0035735Biological processintraciliary transport involved in cilium assembly
GO_0035720Biological processintraciliary anterograde transport
GO_0042073Biological processintraciliary transport
GO_0005813Cellular componentcentrosome
GO_0031514Cellular componentmotile cilium
GO_0030992Cellular componentintraciliary transport particle B
GO_0005814Cellular componentcentriole
GO_0097542Cellular componentciliary tip
GO_0097228Cellular componentsperm principal piece
GO_0005929Cellular componentcilium
GO_0005737Cellular componentcytoplasm
GO_0097225Cellular componentsperm midpiece
GO_0036064Cellular componentciliary basal body
GO_0015631Molecular functiontubulin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameIFT81
Protein nameIFT81 protein
Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)
Intraflagellar transport 81
SynonymsCDV1
DescriptionFUNCTION: Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region . Required for ciliogenesis . Required for proper regulation of SHH signaling . Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella (By similarity). .

AccessionsQ8WYA0
ENST00000552912.5 [Q8WYA0-1]
H0YHE2
Q05DP9
F8W1J4
ENST00000361948.8 [Q8WYA0-3]
ENST00000550156.5
ENST00000546374.5
ENST00000242591.10 [Q8WYA0-1]
H0YIR4
ENST00000551273.1