Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 4 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 97% | 1399.34 | 174 / 180 | 91% | 31.85 | 393 / 430 |
breast | 98% | 1812.82 | 449 / 459 | 84% | 24.75 | 935 / 1118 |
brain | 91% | 1360.52 | 2414 / 2642 | 89% | 30.69 | 624 / 705 |
uterus | 90% | 907.68 | 153 / 170 | 73% | 19.74 | 333 / 459 |
lung | 97% | 1699.18 | 559 / 578 | 65% | 12.86 | 755 / 1155 |
kidney | 92% | 2447.47 | 82 / 89 | 70% | 12.62 | 628 / 901 |
thymus | 99% | 1896.05 | 645 / 653 | 60% | 8.23 | 366 / 605 |
esophagus | 76% | 1060.04 | 1105 / 1445 | 71% | 18.12 | 130 / 183 |
bladder | 86% | 760.76 | 18 / 21 | 52% | 12.11 | 261 / 504 |
adrenal gland | 97% | 1315.72 | 249 / 258 | 32% | 3.19 | 74 / 230 |
intestine | 81% | 826.61 | 782 / 966 | 36% | 5.65 | 189 / 527 |
skin | 62% | 814.87 | 1129 / 1809 | 51% | 11.90 | 243 / 472 |
prostate | 87% | 783.56 | 212 / 245 | 26% | 3.39 | 129 / 502 |
stomach | 57% | 577.67 | 203 / 359 | 50% | 7.69 | 143 / 286 |
spleen | 100% | 3064.12 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 97% | 2036.87 | 1163 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 16% | 110.88 | 54 / 328 | 78% | 15.67 | 139 / 178 |
heart | 92% | 1115.08 | 795 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 86% | 1060.66 | 1147 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 73% | 15.42 | 33 / 45 |
muscle | 52% | 336.11 | 417 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 48% | 10.63 | 14 / 29 |
liver | 25% | 237.54 | 56 / 226 | 18% | 2.53 | 73 / 406 |
peripheral blood | 39% | 8402.10 | 359 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 14% | 1.65 | 11 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006955 | Biological process | immune response |
GO_0051607 | Biological process | defense response to virus |
GO_0005575 | Cellular component | cellular_component |
GO_0005737 | Cellular component | cytoplasm |
GO_0003674 | Molecular function | molecular_function |
Gene name | IFI44L |
Protein name | Interferon-induced protein 44-like Interferon induced protein 44 like Interferon induced protein 44 like (cDNA FLJ50321, highly similar to Homo sapiens interferon-induced protein 44-like (IFI44L), mRNA) (cDNA, FLJ79131, highly similar to Homo sapiens interferon-induced protein 44-like (IFI44L), mRNA) |
Synonyms | C1orf29 GS3686 |
Description | FUNCTION: Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity . During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion . Plays a role in the control of respiratory syncytial virus/RSV infection, reducing the ability of the virus to replicate . Exhibits a low antiviral activity against hepatitis C virus . Acts also as a feedback regulator of IFN responses by negatively regulating IKBKB and IKBKE kinase activities through interaction with FKBP5 . . |
Accessions | A0A7P0T9R5 A0A7P0Z4K2 ENST00000370751.10 [Q53G44-1] ENST00000679848.1 B4E019 ENST00000681613.1 ENST00000476521.5 C9JPJ0 ENST00000679998.1 ENST00000680295.1 ENST00000450498.1 ENST00000452835.1 ENST00000681501.1 ENST00000459784.6 Q53G44 ENST00000680110.1 H7C1K6 |