ICE1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042795Biological processsnRNA transcription by RNA polymerase II
GO_0045945Biological processpositive regulation of transcription by RNA polymerase III
GO_0090316Biological processpositive regulation of intracellular protein transport
GO_0042796Biological processsnRNA transcription by RNA polymerase III
GO_0031334Biological processpositive regulation of protein-containing complex assembly
GO_0015030Cellular componentCajal body
GO_0000791Cellular componenteuchromatin
GO_0035363Cellular componenthistone locus body
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0008023Cellular componenttranscription elongation factor complex
GO_0030674Molecular functionprotein-macromolecule adaptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameICE1
Protein nameInteractor of little elongation complex ELL subunit 1
Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1)
SynonymsKIAA0947
DescriptionFUNCTION: Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III . Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies . .

AccessionsA0A096LPH9
ENST00000296564.9
ENST00000512608.5
Q9Y2F5