HTR5A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HTR5A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HTR5A at tissue level.

III. Associated gene sets

GO_0032355Biological processresponse to estradiol
GO_0007198Biological processadenylate cyclase-inhibiting serotonin receptor signaling pathway
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0021766Biological processhippocampus development
GO_0007268Biological processchemical synaptic transmission
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0043204Cellular componentperikaryon
GO_0030425Cellular componentdendrite
GO_0005886Cellular componentplasma membrane
GO_0099634Cellular componentpostsynaptic specialization membrane
GO_0051378Molecular functionserotonin binding
GO_0004993Molecular functionG protein-coupled serotonin receptor activity
GO_0030594Molecular functionneurotransmitter receptor activity

IV. Literature review

[source]
Gene nameHTR5A
Protein name5-hydroxytryptamine (Serotonin) receptor 5A
5-hydroxytryptamine receptor 5A (5-HT-5) (5-HT-5A) (5-HT5A) (Serotonin receptor 5A)
Uncharacterized protein HTR5A
5-hydroxytryptamine (Serotonin) receptor 5A (cDNA FLJ36936 fis, clone BRACE2005395, highly similar to 5-HYDROXYTRYPTAMINE 5A RECEPTOR)
5-hydroxytryptamine receptor 5A
Synonymstcag7.833
hCG_17152
DescriptionFUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.

AccessionsQ86UN1
P47898
Q14D80
A4D2N2
ENST00000287907.3
Q75LH0
ENST00000649716.1
A0A3B3ISH0