Insufficient scRNA-seq data for expression of HTR3A at single-cell level.
Insufficient scRNA-seq data for expression of HTR3A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 81% | 170.53 | 266 / 328 | 48% | 2.14 | 85 / 178 |
intestine | 96% | 195.73 | 923 / 966 | 15% | 1.63 | 79 / 527 |
ovary | 0% | 0 | 0 / 180 | 89% | 41.26 | 382 / 430 |
spleen | 88% | 53.67 | 211 / 241 | 0% | 0 | 0 / 0 |
stomach | 67% | 67.20 | 242 / 359 | 17% | 1.37 | 50 / 286 |
esophagus | 53% | 47.19 | 773 / 1445 | 25% | 0.89 | 46 / 183 |
lymph node | 0% | 0 | 0 / 0 | 76% | 70.96 | 22 / 29 |
brain | 58% | 79.00 | 1540 / 2642 | 4% | 0.06 | 26 / 705 |
lung | 13% | 5.74 | 73 / 578 | 47% | 6.26 | 540 / 1155 |
skin | 40% | 31.64 | 721 / 1809 | 7% | 0.35 | 34 / 472 |
bladder | 24% | 12.71 | 5 / 21 | 11% | 2.21 | 57 / 504 |
kidney | 17% | 6.88 | 15 / 89 | 14% | 1.05 | 125 / 901 |
adrenal gland | 15% | 6.79 | 38 / 258 | 13% | 1.49 | 31 / 230 |
uterus | 2% | 0.45 | 3 / 170 | 24% | 2.71 | 109 / 459 |
tonsil | 0% | 0 | 0 / 0 | 22% | 1.15 | 10 / 45 |
thymus | 10% | 6.52 | 66 / 653 | 12% | 0.90 | 71 / 605 |
peripheral blood | 16% | 4.94 | 152 / 929 | 0% | 0 | 0 / 0 |
breast | 6% | 3.13 | 29 / 459 | 10% | 0.70 | 112 / 1118 |
liver | 3% | 0.83 | 6 / 226 | 10% | 1.29 | 40 / 406 |
prostate | 7% | 3.08 | 17 / 245 | 4% | 0.09 | 18 / 502 |
heart | 4% | 1.18 | 36 / 861 | 0% | 0 | 0 / 0 |
muscle | 2% | 0.56 | 14 / 803 | 0% | 0 | 0 / 0 |
adipose | 2% | 0.52 | 19 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 0.41 | 18 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_0034220 | Biological process | monoatomic ion transmembrane transport |
GO_0007210 | Biological process | serotonin receptor signaling pathway |
GO_0098662 | Biological process | inorganic cation transmembrane transport |
GO_0099505 | Biological process | regulation of presynaptic membrane potential |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_1904602 | Cellular component | serotonin-activated cation-selective channel complex |
GO_0005886 | Cellular component | plasma membrane |
GO_1902495 | Cellular component | transmembrane transporter complex |
GO_0043005 | Cellular component | neuron projection |
GO_0045202 | Cellular component | synapse |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0032154 | Cellular component | cleavage furrow |
GO_0022850 | Molecular function | serotonin-gated monoatomic cation channel activity |
GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO_0005231 | Molecular function | excitatory extracellular ligand-gated monoatomic ion channel activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0051378 | Molecular function | serotonin binding |
GO_0099507 | Molecular function | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
GO_0005515 | Molecular function | protein binding |
Gene name | HTR3A |
Protein name | 5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor) 5-hydroxytryptamine receptor 3A 5-hydroxytryptamine (Serotonin) receptor 3A |
Synonyms | 5HT3R HTR3 |
Description | FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. . |
Accessions | ENST00000504030.7 [P46098-1] B3VRH0 ENST00000510849.5 B3VRK0 ENST00000355556.6 [P46098-5] B3VRI0 B3VRH5 ENST00000299961.5 [P46098-3] ENST00000506841.6 [P46098-2] P46098 B3VRG0 B3VRJ0 B3VRG5 B3VRJ5 B3VRI5 ENST00000375498.6 [P46098-4] A0A0B4J205 |