HTR3A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HTR3A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HTR3A at tissue level.

III. Associated gene sets

GO_0042391Biological processregulation of membrane potential
GO_0060079Biological processexcitatory postsynaptic potential
GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0007210Biological processserotonin receptor signaling pathway
GO_0098662Biological processinorganic cation transmembrane transport
GO_0099505Biological processregulation of presynaptic membrane potential
GO_0007268Biological processchemical synaptic transmission
GO_1904602Cellular componentserotonin-activated cation-selective channel complex
GO_0005886Cellular componentplasma membrane
GO_1902495Cellular componenttransmembrane transporter complex
GO_0043005Cellular componentneuron projection
GO_0045202Cellular componentsynapse
GO_0045211Cellular componentpostsynaptic membrane
GO_0032154Cellular componentcleavage furrow
GO_0022850Molecular functionserotonin-gated monoatomic cation channel activity
GO_1904315Molecular functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO_0005231Molecular functionexcitatory extracellular ligand-gated monoatomic ion channel activity
GO_0042802Molecular functionidentical protein binding
GO_0051378Molecular functionserotonin binding
GO_0099507Molecular functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHTR3A
Protein name5-hydroxytryptamine receptor 3A (5-HT3-A) (5-HT3A) (5-hydroxytryptamine receptor 3) (5-HT-3) (5-HT3R) (Serotonin receptor 3A) (Serotonin-gated ion channel receptor)
5-hydroxytryptamine receptor 3A
5-hydroxytryptamine (Serotonin) receptor 3A
Synonyms5HT3R
HTR3
DescriptionFUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. .

AccessionsENST00000504030.7 [P46098-1]
B3VRH0
ENST00000510849.5
B3VRK0
ENST00000355556.6 [P46098-5]
B3VRI0
B3VRH5
ENST00000299961.5 [P46098-3]
ENST00000506841.6 [P46098-2]
P46098
B3VRG0
B3VRJ0
B3VRG5
B3VRJ5
B3VRI5
ENST00000375498.6 [P46098-4]
A0A0B4J205