HR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HR at tissue level.

III. Associated gene sets

GO_0006338Biological processchromatin remodeling
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000118Cellular componenthistone deacetylase complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0031490Molecular functionchromatin DNA binding
GO_0140683Molecular functionhistone H3K9me/H3K9me2 demethylase activity
GO_0032454Molecular functionhistone H3K9 demethylase activity
GO_0005515Molecular functionprotein binding
GO_0003712Molecular functiontranscription coregulator activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameHR
Protein nameLysine-specific demethylase hairless (EC 1.14.11.65) ([histone H3]-dimethyl-L-lysine(9) demethylase hairless)
HR lysine demethylase and nuclear receptor corepressor
Truncated hair growth associated
Hair growth associated
Synonyms
DescriptionFUNCTION: Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle. .

AccessionsA0A0A0WJ87
ENST00000381418.9 [O43593-1]
A0A0A0WDA6
A0A0A0WDV7
O43593
A0A0A0WEW9
ENST00000517699.2
ENST00000680789.1 [O43593-1]
ENST00000312841.9 [O43593-2]
E5RK80