HPX | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	6 studies	82% ± 20%	Explore
endothelial cell	3 studies	39% ± 13%	Explore

Name	Number of supported studies	Average coverage
liver	4 studies	45% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	172018.82	226 / 226	99%	1462.41	400 / 406
prostate	100%	250.64	244 / 245	90%	3.00	453 / 502
breast	98%	558.89	452 / 459	87%	26.32	976 / 1118
pancreas	96%	295.80	315 / 328	42%	1.02	74 / 178
adrenal gland	95%	68.58	244 / 258	33%	1.13	76 / 230
lung	99%	124.40	572 / 578	25%	1.06	291 / 1155
uterus	100%	125.89	170 / 170	22%	0.58	99 / 459
brain	85%	101.25	2255 / 2642	35%	0.67	248 / 705
intestine	99%	117.82	953 / 966	21%	6.18	113 / 527
kidney	92%	66.91	82 / 89	23%	1.11	207 / 901
skin	100%	142.44	1805 / 1809	13%	0.32	60 / 472
stomach	95%	71.48	341 / 359	17%	0.44	48 / 286
bladder	95%	109.05	20 / 21	16%	0.37	82 / 504
ovary	99%	151.74	178 / 180	12%	0.20	52 / 430
thymus	99%	102.94	644 / 653	8%	0.13	49 / 605
esophagus	89%	74.78	1289 / 1445	12%	1.25	22 / 183
blood vessel	99%	120.88	1323 / 1335	0%	0	0 / 0
spleen	99%	399.10	238 / 241	0%	0	0 / 0
adipose	96%	113.25	1158 / 1204	0%	0	0 / 0
heart	69%	43.89	593 / 861	0%	0	0 / 0
peripheral blood	37%	33.03	346 / 929	0%	0	0 / 0
muscle	33%	14.18	268 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.12	3 / 45
lymph node	0%	0	0 / 0	3%	0.04	1 / 29
eye	0%	0	0 / 0	3%	0.04	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042531	Biological process	positive regulation of tyrosine phosphorylation of STAT protein
GO_0060335	Biological process	positive regulation of type II interferon-mediated signaling pathway
GO_0060333	Biological process	type II interferon-mediated signaling pathway
GO_0020027	Biological process	hemoglobin metabolic process
GO_0042168	Biological process	heme metabolic process
GO_0002639	Biological process	positive regulation of immunoglobulin production
GO_0006879	Biological process	intracellular iron ion homeostasis
GO_0002925	Biological process	positive regulation of humoral immune response mediated by circulating immunoglobulin
GO_0015886	Biological process	heme transport
GO_0005615	Cellular component	extracellular space
GO_0071682	Cellular component	endocytic vesicle lumen
GO_0072562	Cellular component	blood microparticle
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0015232	Molecular function	heme transmembrane transporter activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

Gene name	HPX
Protein name	Hemopexin (Beta-1B-glycoprotein)
Synonyms
Description	FUNCTION: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Accessions	P02790 ENST00000265983.8

HPX report