HOXA9 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HOXA9 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HOXA9 at tissue level.

III. Associated gene sets

GO_0033574Biological processresponse to testosterone
GO_0030879Biological processmammary gland development
GO_0045638Biological processnegative regulation of myeloid cell differentiation
GO_0009954Biological processproximal/distal pattern formation
GO_0007283Biological processspermatogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0048704Biological processembryonic skeletal system morphogenesis
GO_0030850Biological processprostate gland development
GO_0042118Biological processendothelial cell activation
GO_0035115Biological processembryonic forelimb morphogenesis
GO_0006351Biological processDNA-templated transcription
GO_0060216Biological processdefinitive hemopoiesis
GO_0060065Biological processuterus development
GO_0009952Biological processanterior/posterior pattern specification
GO_0008584Biological processmale gonad development
GO_0007338Biological processsingle fertilization
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005737Cellular componentcytoplasm
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0019899Molecular functionenzyme binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHOXA9
Protein nameHomeobox protein Hox-A9 (Homeobox protein Hox-1G)
Homeobox A9
SynonymsHOX1G
DescriptionFUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation . Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH (By similarity). .

AccessionsA0A669KBC8
ENST00000343483.7
A8MVF3
P31269
ENST00000673744.1
ENST00000396345.1
ENST00000673917.1
A0A669K9T0