HOOK2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007040Biological processlysosome organization
GO_0006897Biological processendocytosis
GO_0031122Biological processcytoplasmic microtubule organization
GO_1905719Biological processprotein localization to perinuclear region of cytoplasm
GO_0008333Biological processendosome to lysosome transport
GO_0007032Biological processendosome organization
GO_0015031Biological processprotein transport
GO_0045022Biological processearly endosome to late endosome transport
GO_0030705Biological processcytoskeleton-dependent intracellular transport
GO_0030897Cellular componentHOPS complex
GO_0005874Cellular componentmicrotubule
GO_0005813Cellular componentcentrosome
GO_0070695Cellular componentFHF complex
GO_0005802Cellular componenttrans-Golgi network
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0042802Molecular functionidentical protein binding
GO_0008017Molecular functionmicrotubule binding
GO_0051959Molecular functiondynein light intermediate chain binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHOOK2
Protein nameProtein Hook homolog 2 (h-hook2) (hHK2)
Hook microtubule tethering protein 2
Synonyms
DescriptionFUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell . .

AccessionsENST00000586188.5
K7EJ65
ENST00000588052.5
ENST00000264827.9 [Q96ED9-2]
ENST00000678590.1
ENST00000590839.5
K7ENU5
K7EJA7
ENST00000592079.5
K7EK29
ENST00000397668.8 [Q96ED9-1]
ENST00000587178.1
K7EMR5
K7EJ48
K7EMG7
A0A7I2V5Y2
ENST00000586719.5
ENST00000589400.5
Q96ED9