Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 16 studies | 27% ± 16% | |
epithelial cell | 10 studies | 38% ± 20% | |
adipocyte | 10 studies | 59% ± 17% | |
club cell | 9 studies | 25% ± 9% | |
type I pneumocyte | 9 studies | 24% ± 7% | |
type II pneumocyte | 7 studies | 32% ± 12% | |
ciliated cell | 7 studies | 27% ± 4% | |
goblet cell | 7 studies | 30% ± 15% | |
enterocyte | 6 studies | 29% ± 6% | |
endothelial cell | 6 studies | 29% ± 7% | |
glutamatergic neuron | 6 studies | 47% ± 20% | |
fibroblast | 6 studies | 18% ± 3% | |
astrocyte | 6 studies | 29% ± 6% | |
GABAergic neuron | 6 studies | 41% ± 19% | |
amacrine cell | 5 studies | 29% ± 6% | |
cardiac muscle cell | 5 studies | 53% ± 12% | |
interneuron | 5 studies | 39% ± 21% | |
retinal bipolar neuron | 4 studies | 27% ± 4% | |
retinal ganglion cell | 4 studies | 27% ± 5% | |
retinal cone cell | 4 studies | 22% ± 5% | |
mucus secreting cell | 4 studies | 29% ± 8% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 23% ± 4% | |
oligodendrocyte precursor cell | 4 studies | 30% ± 10% | |
brush cell | 4 studies | 20% ± 3% | |
respiratory goblet cell | 4 studies | 34% ± 12% | |
abnormal cell | 4 studies | 27% ± 8% | |
secretory cell | 3 studies | 26% ± 3% | |
pancreatic A cell | 3 studies | 25% ± 5% | |
microglial cell | 3 studies | 19% ± 3% | |
serous secreting cell | 3 studies | 18% ± 3% | |
Mueller cell | 3 studies | 20% ± 2% | |
rod bipolar cell | 3 studies | 25% ± 5% | |
enteroendocrine cell | 3 studies | 31% ± 12% | |
macrophage | 3 studies | 21% ± 2% | |
transit amplifying cell | 3 studies | 34% ± 26% | |
neuron | 3 studies | 37% ± 8% | |
oligodendrocyte | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2439.24 | 21 / 21 | 100% | 27.17 | 503 / 504 |
thymus | 100% | 9647.53 | 653 / 653 | 100% | 33.11 | 603 / 605 |
pancreas | 100% | 5141.43 | 328 / 328 | 99% | 26.07 | 177 / 178 |
prostate | 100% | 5235.98 | 245 / 245 | 99% | 33.79 | 499 / 502 |
intestine | 99% | 2898.35 | 960 / 966 | 100% | 26.49 | 525 / 527 |
ovary | 99% | 2353.86 | 179 / 180 | 100% | 31.38 | 428 / 430 |
uterus | 99% | 1899.48 | 169 / 170 | 99% | 27.32 | 456 / 459 |
stomach | 99% | 2982.12 | 356 / 359 | 99% | 22.52 | 284 / 286 |
breast | 100% | 4946.50 | 459 / 459 | 98% | 25.97 | 1100 / 1118 |
lung | 99% | 2472.26 | 571 / 578 | 99% | 24.11 | 1142 / 1155 |
kidney | 100% | 4464.30 | 89 / 89 | 94% | 15.34 | 849 / 901 |
esophagus | 94% | 2543.81 | 1353 / 1445 | 99% | 22.21 | 182 / 183 |
liver | 100% | 2295.98 | 225 / 226 | 72% | 11.35 | 294 / 406 |
skin | 97% | 3802.27 | 1756 / 1809 | 74% | 7.04 | 351 / 472 |
brain | 78% | 1195.51 | 2048 / 2642 | 94% | 12.80 | 662 / 705 |
adrenal gland | 99% | 1905.95 | 256 / 258 | 70% | 6.40 | 162 / 230 |
spleen | 100% | 1654.63 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.14 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.44 | 1 / 1 |
adipose | 100% | 4113.86 | 1200 / 1204 | 0% | 0 | 0 / 0 |
muscle | 96% | 2129.11 | 769 / 803 | 0% | 0 | 0 / 0 |
heart | 92% | 2657.63 | 788 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 90% | 1518.97 | 1200 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 76% | 6.04 | 22 / 29 |
eye | 0% | 0 | 0 / 0 | 55% | 4.25 | 44 / 80 |
peripheral blood | 41% | 386.88 | 382 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007040 | Biological process | lysosome organization |
GO_0006897 | Biological process | endocytosis |
GO_0031122 | Biological process | cytoplasmic microtubule organization |
GO_1905719 | Biological process | protein localization to perinuclear region of cytoplasm |
GO_0008333 | Biological process | endosome to lysosome transport |
GO_0007032 | Biological process | endosome organization |
GO_0015031 | Biological process | protein transport |
GO_0045022 | Biological process | early endosome to late endosome transport |
GO_0030705 | Biological process | cytoskeleton-dependent intracellular transport |
GO_0030897 | Cellular component | HOPS complex |
GO_0005874 | Cellular component | microtubule |
GO_0005813 | Cellular component | centrosome |
GO_0070695 | Cellular component | FHF complex |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0042802 | Molecular function | identical protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0051959 | Molecular function | dynein light intermediate chain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | HOOK2 |
Protein name | Protein Hook homolog 2 (h-hook2) (hHK2) Hook microtubule tethering protein 2 |
Synonyms | |
Description | FUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell . . |
Accessions | ENST00000586188.5 K7EJ65 ENST00000588052.5 ENST00000264827.9 [Q96ED9-2] ENST00000678590.1 ENST00000590839.5 K7ENU5 K7EJA7 ENST00000592079.5 K7EK29 ENST00000397668.8 [Q96ED9-1] ENST00000587178.1 K7EMR5 K7EJ48 K7EMG7 A0A7I2V5Y2 ENST00000586719.5 ENST00000589400.5 Q96ED9 |