Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 36 studies | 37% ± 13% | |
| classical monocyte | 21 studies | 26% ± 8% | |
| fibroblast | 18 studies | 22% ± 7% | |
| monocyte | 15 studies | 27% ± 7% | |
| non-classical monocyte | 15 studies | 23% ± 7% | |
| myeloid cell | 11 studies | 30% ± 10% | |
| epithelial cell | 11 studies | 35% ± 19% | |
| club cell | 9 studies | 34% ± 17% | |
| alveolar macrophage | 8 studies | 37% ± 12% | |
| pericyte | 7 studies | 20% ± 3% | |
| connective tissue cell | 7 studies | 23% ± 7% | |
| mononuclear phagocyte | 6 studies | 29% ± 11% | |
| epithelial cell of proximal tubule | 6 studies | 26% ± 8% | |
| ciliated cell | 6 studies | 25% ± 6% | |
| dendritic cell | 6 studies | 27% ± 8% | |
| conventional dendritic cell | 6 studies | 24% ± 7% | |
| microglial cell | 6 studies | 24% ± 5% | |
| adipocyte | 5 studies | 35% ± 14% | |
| hepatocyte | 5 studies | 48% ± 25% | |
| goblet cell | 5 studies | 19% ± 4% | |
| myofibroblast cell | 4 studies | 17% ± 1% | |
| oligodendrocyte precursor cell | 4 studies | 24% ± 6% | |
| respiratory goblet cell | 4 studies | 41% ± 22% | |
| kidney loop of Henle epithelial cell | 3 studies | 17% ± 1% | |
| leukocyte | 3 studies | 18% ± 1% | |
| abnormal cell | 3 studies | 27% ± 14% | |
| smooth muscle cell | 3 studies | 21% ± 2% | |
| astrocyte | 3 studies | 27% ± 6% | |
| intermediate monocyte | 3 studies | 34% ± 8% | |
| inflammatory macrophage | 3 studies | 26% ± 5% | |
| GABAergic neuron | 3 studies | 21% ± 5% | |
| intestinal crypt stem cell | 3 studies | 28% ± 3% | |
| basal cell | 3 studies | 26% ± 8% | |
| luminal hormone-sensing cell of mammary gland | 3 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 3677.62 | 225 / 226 | 100% | 61.96 | 405 / 406 |
| breast | 100% | 3323.95 | 459 / 459 | 98% | 33.09 | 1097 / 1118 |
| intestine | 100% | 2017.51 | 964 / 966 | 97% | 33.49 | 512 / 527 |
| stomach | 99% | 1345.67 | 356 / 359 | 98% | 31.02 | 279 / 286 |
| prostate | 99% | 1937.73 | 243 / 245 | 97% | 27.56 | 487 / 502 |
| kidney | 100% | 2686.74 | 89 / 89 | 95% | 49.79 | 858 / 901 |
| brain | 94% | 939.00 | 2486 / 2642 | 100% | 54.18 | 702 / 705 |
| pancreas | 95% | 1025.48 | 313 / 328 | 96% | 35.51 | 171 / 178 |
| lung | 100% | 1994.91 | 576 / 578 | 89% | 25.69 | 1026 / 1155 |
| bladder | 100% | 2107.24 | 21 / 21 | 87% | 27.96 | 439 / 504 |
| ovary | 100% | 4196.68 | 180 / 180 | 75% | 11.36 | 322 / 430 |
| skin | 95% | 1559.36 | 1722 / 1809 | 78% | 16.05 | 367 / 472 |
| esophagus | 94% | 1021.65 | 1360 / 1445 | 61% | 11.43 | 111 / 183 |
| uterus | 100% | 3006.46 | 170 / 170 | 55% | 12.10 | 251 / 459 |
| thymus | 96% | 1085.17 | 629 / 653 | 53% | 6.78 | 319 / 605 |
| adrenal gland | 81% | 630.19 | 208 / 258 | 27% | 3.70 | 62 / 230 |
| blood vessel | 100% | 2928.52 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1788.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.65 | 1 / 1 |
| adipose | 100% | 3984.89 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 14.92 | 26 / 29 |
| heart | 76% | 765.73 | 653 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 56% | 12.57 | 45 / 80 |
| peripheral blood | 31% | 223.86 | 291 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 2.42 | 11 / 45 |
| muscle | 14% | 78.94 | 113 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001692 | Biological process | histamine metabolic process |
| GO_0001695 | Biological process | histamine catabolic process |
| GO_0032259 | Biological process | methylation |
| GO_0006548 | Biological process | L-histidine catabolic process |
| GO_0007585 | Biological process | respiratory gaseous exchange by respiratory system |
| GO_0005813 | Cellular component | centrosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0046539 | Molecular function | histamine N-methyltransferase activity |
| Gene name | HNMT |
| Protein name | Histamine N-methyltransferase (EC 2.1.1.8) Histamine N-methyltransferase (HMT) (EC 2.1.1.8) |
| Synonyms | |
| Description | FUNCTION: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. . FUNCTION: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. . |
| Accessions | ENST00000280097.5 [P50135-1] ENST00000280096.5 [P50135-3] ENST00000410115.5 [P50135-1] P50135 ENST00000329366.8 [P50135-2] ENST00000475675.5 [P50135-3] Q9P1Y0 |