Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 6 studies | 29% ± 8% | |
| epithelial cell | 4 studies | 37% ± 16% | |
| astrocyte | 4 studies | 27% ± 9% | |
| erythroblast | 4 studies | 39% ± 15% | |
| GABAergic neuron | 3 studies | 27% ± 4% | |
| glutamatergic neuron | 3 studies | 29% ± 5% | |
| erythrocyte | 3 studies | 33% ± 14% |
Insufficient scRNA-seq data for expression of HMGN5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 724.92 | 653 / 653 | 100% | 24.11 | 604 / 605 |
| adrenal gland | 100% | 966.31 | 258 / 258 | 98% | 23.88 | 225 / 230 |
| brain | 96% | 794.33 | 2545 / 2642 | 98% | 32.79 | 694 / 705 |
| kidney | 100% | 737.10 | 89 / 89 | 92% | 10.34 | 832 / 901 |
| breast | 100% | 455.86 | 459 / 459 | 92% | 15.28 | 1030 / 1118 |
| prostate | 100% | 648.18 | 245 / 245 | 87% | 10.15 | 439 / 502 |
| ovary | 100% | 763.94 | 180 / 180 | 82% | 10.10 | 353 / 430 |
| pancreas | 94% | 240.41 | 309 / 328 | 87% | 8.46 | 154 / 178 |
| intestine | 100% | 601.65 | 966 / 966 | 79% | 10.95 | 418 / 527 |
| stomach | 100% | 437.43 | 358 / 359 | 75% | 10.91 | 214 / 286 |
| uterus | 100% | 752.25 | 170 / 170 | 71% | 17.66 | 327 / 459 |
| bladder | 100% | 569.00 | 21 / 21 | 69% | 8.11 | 350 / 504 |
| lung | 98% | 364.41 | 567 / 578 | 69% | 8.55 | 801 / 1155 |
| esophagus | 100% | 630.46 | 1444 / 1445 | 67% | 8.68 | 123 / 183 |
| skin | 91% | 229.71 | 1651 / 1809 | 75% | 10.44 | 353 / 472 |
| liver | 98% | 458.16 | 222 / 226 | 49% | 4.84 | 197 / 406 |
| spleen | 100% | 550.20 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 570.41 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 378.82 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| heart | 83% | 234.28 | 711 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 67% | 10.06 | 30 / 45 |
| muscle | 63% | 121.65 | 509 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 3.15 | 9 / 29 |
| eye | 0% | 0 | 0 / 0 | 24% | 1.53 | 19 / 80 |
| peripheral blood | 20% | 476.23 | 188 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005634 | Cellular component | nucleus |
| GO_0003723 | Molecular function | RNA binding |
| GO_0031492 | Molecular function | nucleosomal DNA binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | HMGN5 |
| Protein name | High mobility group nucleosome binding domain 5 High mobility group nucleosome-binding domain-containing protein 5 (Nucleosome-binding protein 1) |
| Synonyms | NSBP1 |
| Description | FUNCTION: Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. . |
| Accessions | ENST00000430960.5 Q5JSK9 ENST00000358130.7 P82970 Q5JSK8 ENST00000451455.1 Q5JSL0 ENST00000373250.7 Q5JSK7 ENST00000447319.5 Q5JSK6 ENST00000436386.5 |
