HES2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HES2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HES2 at tissue level.

III. Associated gene sets

GO_0050767Biological processregulation of neurogenesis
GO_0009952Biological processanterior/posterior pattern specification
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHES2
Protein nameTranscription factor HES-2 (Class B basic helix-loop-helix protein 40) (bHLHb40) (Hairy and enhancer of split 2)
Hes family bHLH transcription factor 2
SynonymsBHLHB40
DescriptionFUNCTION: Transcriptional repressor of genes that require a bHLH protein for their transcription. .

AccessionsQ9Y543
ENST00000377834.8 [Q9Y543-1]
ENST00000377837.5 [Q9Y543-2]
K7EJN2
ENST00000487437.5
ENST00000489730.1
ENST00000377836.8 [Q9Y543-2]
K7EJQ0