HENMT1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HENMT1 at tissue level.

III. Associated gene sets

GO_0034587Biological processpiRNA processing
GO_0001510Biological processRNA methylation
GO_0030422Biological processsiRNA processing
GO_0043186Cellular componentP granule
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0008171Molecular functionO-methyltransferase activity
GO_0008173Molecular functionRNA methyltransferase activity
GO_0090486Molecular functionsmall RNA 2'-O-methyltransferase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameHENMT1
Protein nameSmall RNA 2'-O-methyltransferase (EC 2.1.1.386) (HEN1 methyltransferase homolog 1)
SynonymsC1orf59
DescriptionFUNCTION: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. .

AccessionsA0A0A0MRN1
ENST00000370031.5
ENST00000651461.1
ENST00000420055.1
ENST00000370032.9
ENST00000402983.5
X6RGV9
Q5T8I9