HELT report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HELT at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HELT at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0009791Biological processpost-embryonic development
GO_0021858Biological processGABAergic neuron differentiation in basal ganglia
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0035264Biological processmulticellular organism growth
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0009952Biological processanterior/posterior pattern specification
GO_0007417Biological processcentral nervous system development
GO_0050767Biological processregulation of neurogenesis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0001967Biological processsuckling behavior
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0042802Molecular functionidentical protein binding
GO_0046983Molecular functionprotein dimerization activity

IV. Literature review

[source]
Gene nameHELT
Protein nameHelt bHLH transcription factor
Hairy and enhancer of split-related protein HELT (HES/HEY-like transcription factor)
Synonyms
DescriptionFUNCTION: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'. .

AccessionsENST00000505610.5 [A6NFD8-4]
ENST00000338875.5
A6NFD8
A0A087WSW0
ENST00000515777.6 [A6NFD8-3]