HEATR5B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0015031Biological processprotein transport
GO_0008104Biological processprotein localization
GO_0006897Biological processendocytosis
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016607Cellular componentnuclear speck
GO_0005829Cellular componentcytosol
GO_0030136Cellular componentclathrin-coated vesicle
GO_0030139Cellular componentendocytic vesicle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHEATR5B
Protein nameHEAT repeat-containing protein 5B
HEAT repeat containing 5B
SynonymsKIAA1414
p200a
p200
DescriptionFUNCTION: Component of clathrin-coated vesicles . Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes . .

AccessionsENST00000233099.6 [Q9P2D3-1]
H7C2X3
Q9P2D3
ENST00000425467.5
B9EK47