HCRTR2 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	3 studies	33% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HCRTR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	72%	19.48	1898 / 2642	2%	0.04	12 / 705
ovary	61%	6.77	109 / 180	2%	0.10	9 / 430
lung	57%	4.46	328 / 578	3%	0.10	36 / 1155
heart	57%	6.53	495 / 861	0%	0	0 / 0
adrenal gland	16%	0.90	40 / 258	21%	3.01	49 / 230
kidney	36%	3.21	32 / 89	0%	0.02	3 / 901
adipose	33%	2.48	396 / 1204	0%	0	0 / 0
breast	19%	1.20	86 / 459	4%	0.31	48 / 1118
uterus	15%	0.72	25 / 170	5%	0.29	22 / 459
muscle	14%	0.76	116 / 803	0%	0	0 / 0
skin	10%	0.48	187 / 1809	1%	0.01	4 / 472
intestine	10%	0.55	99 / 966	0%	0	0 / 527
blood vessel	9%	0.74	126 / 1335	0%	0	0 / 0
thymus	7%	0.31	47 / 653	0%	0	0 / 605
prostate	7%	0.28	16 / 245	0%	0.01	2 / 502
liver	7%	0.26	15 / 226	0%	0.00	1 / 406
esophagus	6%	0.30	89 / 1445	1%	0.01	1 / 183
stomach	5%	0.25	17 / 359	2%	0.03	5 / 286
bladder	5%	0.38	1 / 21	1%	0.02	3 / 504
pancreas	3%	0.14	9 / 328	1%	0.01	1 / 178
spleen	2%	0.13	6 / 241	0%	0	0 / 0
peripheral blood	1%	0.04	7 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007631	Biological process	feeding behavior
GO_0051480	Biological process	regulation of cytosolic calcium ion concentration
GO_0007218	Biological process	neuropeptide signaling pathway
GO_0032870	Biological process	cellular response to hormone stimulus
GO_0040011	Biological process	locomotion
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0007268	Biological process	chemical synaptic transmission
GO_0010840	Biological process	regulation of circadian sleep/wake cycle, wakefulness
GO_0022410	Biological process	circadian sleep/wake cycle process
GO_0045202	Cellular component	synapse
GO_0005886	Cellular component	plasma membrane
GO_0042277	Molecular function	peptide binding
GO_0017046	Molecular function	peptide hormone binding
GO_0008188	Molecular function	neuropeptide receptor activity
GO_0005515	Molecular function	protein binding
GO_0016499	Molecular function	orexin receptor activity

Gene name	HCRTR2
Protein name	Orexin type-2 receptor isoform 2 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Orexin receptor type 2 (Hypocretin receptor type 2)
Synonyms
Description	FUNCTION: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides . Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding . .
Accessions	O43614 S4X0W3 Q548Y0 ENST00000370862.4 S4WX84 ENST00000615358.4

HCRTR2 report