Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 7 studies | 24% ± 6% | |
epithelial cell | 7 studies | 27% ± 10% | |
neuron | 5 studies | 26% ± 10% | |
glutamatergic neuron | 5 studies | 41% ± 24% | |
CD4-positive, alpha-beta T cell | 4 studies | 17% ± 2% | |
regulatory T cell | 4 studies | 19% ± 4% | |
natural killer cell | 4 studies | 19% ± 2% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 3 studies | 17% ± 2% | |
retinal ganglion cell | 3 studies | 59% ± 23% | |
fibroblast | 3 studies | 23% ± 7% | |
ciliated cell | 3 studies | 25% ± 3% | |
GABAergic neuron | 3 studies | 43% ± 15% | |
astrocyte | 3 studies | 23% ± 4% | |
oligodendrocyte precursor cell | 3 studies | 24% ± 5% | |
CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
dendritic cell | 3 studies | 28% ± 8% | |
basal cell | 3 studies | 28% ± 7% | |
interneuron | 3 studies | 34% ± 20% | |
oligodendrocyte | 3 studies | 20% ± 4% | |
plasmacytoid dendritic cell | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3198.52 | 21 / 21 | 100% | 13.47 | 504 / 504 |
esophagus | 100% | 3440.52 | 1445 / 1445 | 100% | 9.64 | 183 / 183 |
prostate | 100% | 3476.95 | 245 / 245 | 100% | 14.53 | 502 / 502 |
skin | 100% | 5003.91 | 1809 / 1809 | 100% | 18.69 | 472 / 472 |
brain | 100% | 4790.85 | 2639 / 2642 | 100% | 18.01 | 705 / 705 |
kidney | 100% | 2525.62 | 89 / 89 | 100% | 14.44 | 899 / 901 |
breast | 100% | 3022.47 | 459 / 459 | 100% | 14.13 | 1115 / 1118 |
lung | 100% | 2903.09 | 577 / 578 | 100% | 11.49 | 1153 / 1155 |
thymus | 100% | 3044.05 | 653 / 653 | 100% | 15.01 | 602 / 605 |
intestine | 100% | 3332.81 | 966 / 966 | 99% | 13.11 | 524 / 527 |
uterus | 100% | 3543.86 | 170 / 170 | 99% | 15.50 | 456 / 459 |
stomach | 100% | 2724.69 | 359 / 359 | 99% | 11.31 | 284 / 286 |
pancreas | 100% | 2343.98 | 327 / 328 | 99% | 13.00 | 177 / 178 |
adrenal gland | 100% | 3499.92 | 258 / 258 | 99% | 18.19 | 227 / 230 |
ovary | 100% | 3103.47 | 180 / 180 | 98% | 8.79 | 423 / 430 |
liver | 100% | 2440.60 | 226 / 226 | 98% | 9.02 | 397 / 406 |
adipose | 100% | 3023.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 18.17 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 19.14 | 29 / 29 |
spleen | 100% | 3319.05 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.93 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.84 | 1 / 1 |
blood vessel | 100% | 3006.97 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2937.06 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 2180.73 | 840 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 1961.51 | 815 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006412 | Biological process | translation |
GO_0032543 | Biological process | mitochondrial translation |
GO_0006427 | Biological process | histidyl-tRNA aminoacylation |
GO_0006418 | Biological process | tRNA aminoacylation for protein translation |
GO_0005739 | Cellular component | mitochondrion |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004821 | Molecular function | histidine-tRNA ligase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005524 | Molecular function | ATP binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | HARS1 |
Protein name | Histidyl-tRNA synthetase Histidine--tRNA ligase, cytoplasmic (Histidyl-tRNA synthetase) Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS) histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase) Histidyl-tRNA synthetase 1 Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) |
Synonyms | hCG_1782886 HRS HARS |
Description | FUNCTION: Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) . Plays a role in axon guidance . . |
Accessions | ENST00000509087.2 ENST00000675366.1 A0A6Q8PFF2 A0A6Q8PFN6 ENST00000676327.1 B4E1C5 P12081 ENST00000415192.6 ENST00000675827.1 ENST00000431330.7 ENST00000504156.7 [P12081-1] ENST00000675204.1 ENST00000675698.1 ENST00000643686.1 A0A2R8YFR1 A0A6Q8PHE3 A0A6Q8PHQ0 ENST00000457527.6 [P12081-4] A0A2R8YCI2 ENST00000512396.6 ENST00000507746.7 ENST00000645491.1 D6RF05 A0A6Q8PF47 B4DDD8 ENST00000675851.1 ENST00000438307.6 [P12081-2] E7ETE2 B3KWE1 A0A6Q8PF07 A0A6Q8PHA5 ENST00000307633.7 [P12081-3] ENST00000646229.1 A0A6Q8PFG9 ENST00000674523.1 |