HARS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006412Biological processtranslation
GO_0032543Biological processmitochondrial translation
GO_0006427Biological processhistidyl-tRNA aminoacylation
GO_0006418Biological processtRNA aminoacylation for protein translation
GO_0005739Cellular componentmitochondrion
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0004821Molecular functionhistidine-tRNA ligase activity
GO_0042802Molecular functionidentical protein binding
GO_0005524Molecular functionATP binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameHARS1
Protein nameHistidyl-tRNA synthetase
Histidine--tRNA ligase, cytoplasmic (Histidyl-tRNA synthetase)
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
histidine--tRNA ligase (EC 6.1.1.21) (Histidyl-tRNA synthetase)
Histidyl-tRNA synthetase 1
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase)
SynonymshCG_1782886
HRS
HARS
DescriptionFUNCTION: Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) . Plays a role in axon guidance . .

AccessionsENST00000509087.2
ENST00000675366.1
A0A6Q8PFF2
A0A6Q8PFN6
ENST00000676327.1
B4E1C5
P12081
ENST00000415192.6
ENST00000675827.1
ENST00000431330.7
ENST00000504156.7 [P12081-1]
ENST00000675204.1
ENST00000675698.1
ENST00000643686.1
A0A2R8YFR1
A0A6Q8PHE3
A0A6Q8PHQ0
ENST00000457527.6 [P12081-4]
A0A2R8YCI2
ENST00000512396.6
ENST00000507746.7
ENST00000645491.1
D6RF05
A0A6Q8PF47
B4DDD8
ENST00000675851.1
ENST00000438307.6 [P12081-2]
E7ETE2
B3KWE1
A0A6Q8PF07
A0A6Q8PHA5
ENST00000307633.7 [P12081-3]
ENST00000646229.1
A0A6Q8PFG9
ENST00000674523.1