H2BC21 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	27% ± 7%	Explore
retinal bipolar neuron	3 studies	44% ± 20%	Explore
amacrine cell	3 studies	28% ± 7%	Explore
platelet	3 studies	21% ± 5%	Explore
hematopoietic stem cell	3 studies	20% ± 3%	Explore
luminal cell of prostate epithelium	3 studies	23% ± 6%	Explore

Name	Number of supported studies	Average coverage
eye	3 studies	30% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	99%	9923.04	243 / 245	100%	311.10	502 / 502
brain	94%	1929.84	2480 / 2642	91%	47.54	642 / 705
esophagus	99%	2826.34	1429 / 1445	84%	51.36	154 / 183
ovary	92%	5593.67	165 / 180	89%	66.08	382 / 430
thymus	87%	1600.38	571 / 653	91%	49.49	548 / 605
adrenal gland	93%	1400.63	240 / 258	83%	62.47	192 / 230
lung	98%	3544.29	564 / 578	78%	46.79	898 / 1155
bladder	95%	2417.19	20 / 21	70%	46.32	354 / 504
breast	68%	1854.19	314 / 459	95%	140.90	1065 / 1118
skin	77%	4830.17	1396 / 1809	72%	39.90	340 / 472
uterus	66%	2192.54	113 / 170	78%	44.95	360 / 459
stomach	90%	2381.33	323 / 359	51%	19.73	147 / 286
kidney	87%	2204.13	77 / 89	50%	17.38	452 / 901
intestine	90%	1959.17	869 / 966	45%	18.65	239 / 527
pancreas	33%	465.68	109 / 328	82%	50.57	146 / 178
liver	68%	797.64	154 / 226	45%	18.14	181 / 406
muscle	100%	3583.83	803 / 803	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	59.92	1 / 1
spleen	97%	2662.05	233 / 241	0%	0	0 / 0
heart	96%	4172.89	825 / 861	0%	0	0 / 0
blood vessel	91%	1655.71	1211 / 1335	0%	0	0 / 0
peripheral blood	83%	5922.84	775 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	79%	35.69	63 / 80
adipose	57%	948.57	690 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	56%	23.38	25 / 45
lymph node	0%	0	0 / 0	28%	6.81	8 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0002227	Biological process	innate immune response in mucosa
GO_0050830	Biological process	defense response to Gram-positive bacterium
GO_0006334	Biological process	nucleosome assembly
GO_0019731	Biological process	antibacterial humoral response
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0030527	Molecular function	structural constituent of chromatin
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

Gene name	H2BC21
Protein name	Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Synonyms	HIST2H2BE H2BFQ
Description	FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Accessions	ENST00000369155.4 Q16778

H2BC21 report