GTF2E2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0005673Cellular componenttranscription factor TFIIE complex
GO_0005669Cellular componenttranscription factor TFIID complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0001097Molecular functionTFIIH-class transcription factor complex binding
GO_0003677Molecular functionDNA binding
GO_0016251Molecular functionRNA polymerase II general transcription initiation factor activity
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameGTF2E2
Protein nameGeneral transcription factor IIE subunit 2
Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2)
SynonymsTF2E2
DescriptionFUNCTION: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. .

FUNCTION: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. .

AccessionsP29084
ENST00000518599.5
ENST00000518445.1
E5RIW4
ENST00000355904.9
E5RH41
E5RK24
ENST00000523499.5