Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 6 studies | 23% ± 4% | |
| epithelial cell | 4 studies | 26% ± 4% | |
| neuron | 3 studies | 22% ± 5% | |
| plasma cell | 3 studies | 24% ± 9% | |
| GABAergic neuron | 3 studies | 44% ± 5% | |
| glutamatergic neuron | 3 studies | 55% ± 4% | |
| astrocyte | 3 studies | 26% ± 7% | |
| oligodendrocyte | 3 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 38% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1988.01 | 1445 / 1445 | 100% | 30.22 | 183 / 183 |
| brain | 100% | 2362.57 | 2638 / 2642 | 100% | 29.35 | 705 / 705 |
| breast | 100% | 2324.36 | 459 / 459 | 100% | 31.43 | 1116 / 1118 |
| ovary | 100% | 2028.01 | 180 / 180 | 100% | 20.37 | 429 / 430 |
| lung | 100% | 1761.84 | 576 / 578 | 100% | 26.14 | 1155 / 1155 |
| prostate | 100% | 1754.50 | 245 / 245 | 99% | 25.94 | 499 / 502 |
| thymus | 100% | 2962.46 | 653 / 653 | 99% | 41.29 | 600 / 605 |
| uterus | 100% | 2398.04 | 170 / 170 | 99% | 23.70 | 453 / 459 |
| bladder | 100% | 2084.29 | 21 / 21 | 98% | 19.91 | 494 / 504 |
| intestine | 100% | 1710.27 | 966 / 966 | 97% | 19.58 | 511 / 527 |
| stomach | 100% | 1357.94 | 358 / 359 | 97% | 21.23 | 278 / 286 |
| pancreas | 98% | 1028.03 | 323 / 328 | 98% | 19.52 | 175 / 178 |
| kidney | 100% | 1250.09 | 89 / 89 | 96% | 20.84 | 869 / 901 |
| skin | 100% | 2624.01 | 1808 / 1809 | 96% | 25.80 | 452 / 472 |
| adrenal gland | 100% | 2082.33 | 258 / 258 | 95% | 18.40 | 219 / 230 |
| liver | 100% | 1179.80 | 226 / 226 | 89% | 11.75 | 362 / 406 |
| adipose | 100% | 2417.10 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3033.92 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 22.35 | 29 / 29 |
| spleen | 100% | 1915.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.91 | 1 / 1 |
| muscle | 100% | 1922.27 | 801 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 24.69 | 44 / 45 |
| heart | 96% | 1070.36 | 824 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 15.07 | 72 / 80 |
| peripheral blood | 89% | 1687.73 | 825 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051123 | Biological process | RNA polymerase II preinitiation complex assembly |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0060261 | Biological process | positive regulation of transcription initiation by RNA polymerase II |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0097550 | Cellular component | transcription preinitiation complex |
| GO_0005669 | Cellular component | transcription factor TFIID complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005672 | Cellular component | transcription factor TFIIA complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000979 | Molecular function | RNA polymerase II core promoter sequence-specific DNA binding |
| GO_0017025 | Molecular function | TBP-class protein binding |
| GO_0016251 | Molecular function | RNA polymerase II general transcription initiation factor activity |
| GO_0001091 | Molecular function | RNA polymerase II general transcription initiation factor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GTF2A1 |
| Protein name | Transcription initiation factor IIA subunit 1 (General transcription factor IIA subunit 1) (TFIIAL) (Transcription initiation factor TFIIA 42 kDa subunit) (TFIIA-42) [Cleaved into: Transcription initiation factor IIA alpha chain (TFIIA p35 subunit); Transcription initiation factor IIA beta chain (TFIIA p19 subunit)] General transcription factor IIA subunit 1 |
| Synonyms | TF2A1 |
| Description | FUNCTION: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. . |
| Accessions | ENST00000434192.2 [P52655-2] ENST00000553612.6 [P52655-1] ENST00000298173.7 J3KNC0 P52655 |
