Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 38 studies | 41% ± 20% | |
| pericyte | 25 studies | 51% ± 27% | |
| endothelial cell | 22 studies | 37% ± 16% | |
| smooth muscle cell | 19 studies | 49% ± 22% | |
| connective tissue cell | 10 studies | 42% ± 18% | |
| capillary endothelial cell | 10 studies | 50% ± 26% | |
| epithelial cell of proximal tubule | 9 studies | 79% ± 15% | |
| endothelial cell of vascular tree | 9 studies | 32% ± 12% | |
| endothelial cell of artery | 8 studies | 52% ± 28% | |
| epithelial cell | 7 studies | 46% ± 29% | |
| kidney loop of Henle epithelial cell | 6 studies | 40% ± 22% | |
| astrocyte | 6 studies | 78% ± 21% | |
| macrophage | 6 studies | 21% ± 4% | |
| vein endothelial cell | 6 studies | 47% ± 24% | |
| adventitial cell | 5 studies | 64% ± 22% | |
| myofibroblast cell | 5 studies | 72% ± 16% | |
| adipocyte | 5 studies | 27% ± 6% | |
| Mueller cell | 5 studies | 80% ± 21% | |
| glomerular endothelial cell | 4 studies | 61% ± 21% | |
| microglial cell | 4 studies | 49% ± 27% | |
| retinal rod cell | 4 studies | 20% ± 3% | |
| pancreatic A cell | 3 studies | 80% ± 5% | |
| hepatic stellate cell | 3 studies | 28% ± 9% | |
| mature NK T cell | 3 studies | 38% ± 29% | |
| renal alpha-intercalated cell | 3 studies | 48% ± 23% | |
| OFF-bipolar cell | 3 studies | 19% ± 2% | |
| ON-bipolar cell | 3 studies | 22% ± 4% | |
| glycinergic amacrine cell | 3 studies | 21% ± 4% | |
| extravillous trophoblast | 3 studies | 60% ± 19% | |
| placental villous trophoblast | 3 studies | 56% ± 25% | |
| amacrine cell | 3 studies | 26% ± 6% | |
| retina horizontal cell | 3 studies | 21% ± 2% | |
| retinal cone cell | 3 studies | 31% ± 7% | |
| retinal pigment epithelial cell | 3 studies | 53% ± 25% | |
| alveolar macrophage | 3 studies | 25% ± 5% | |
| glial cell | 3 studies | 27% ± 8% | |
| basal cell | 3 studies | 25% ± 9% | |
| Schwann cell | 3 studies | 49% ± 21% | |
| hepatocyte | 3 studies | 50% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 98% | 540668.70 | 87 / 89 | 92% | 1850.89 | 830 / 901 |
| thymus | 100% | 285831.13 | 652 / 653 | 89% | 2551.18 | 539 / 605 |
| liver | 58% | 32257.92 | 132 / 226 | 83% | 622.13 | 337 / 406 |
| lung | 99% | 181449.28 | 575 / 578 | 33% | 111.29 | 382 / 1155 |
| adrenal gland | 57% | 24278.86 | 148 / 258 | 53% | 359.88 | 123 / 230 |
| breast | 92% | 226561.51 | 422 / 459 | 15% | 42.84 | 169 / 1118 |
| ovary | 47% | 28328.06 | 85 / 180 | 60% | 468.78 | 256 / 430 |
| adipose | 99% | 303882.49 | 1193 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 86% | 78861.90 | 18 / 21 | 13% | 57.01 | 64 / 504 |
| esophagus | 81% | 71505.82 | 1175 / 1445 | 16% | 35.92 | 30 / 183 |
| eye | 0% | 0 | 0 / 0 | 95% | 877.86 | 76 / 80 |
| blood vessel | 92% | 100809.08 | 1227 / 1335 | 0% | 0 | 0 / 0 |
| heart | 90% | 89674.39 | 776 / 861 | 0% | 0 | 0 / 0 |
| intestine | 72% | 47094.44 | 699 / 966 | 5% | 15.29 | 24 / 527 |
| prostate | 57% | 35689.05 | 139 / 245 | 13% | 27.06 | 66 / 502 |
| uterus | 49% | 26912.70 | 83 / 170 | 17% | 64.61 | 79 / 459 |
| spleen | 64% | 34512.80 | 154 / 241 | 0% | 0 | 0 / 0 |
| muscle | 59% | 31432.66 | 476 / 803 | 0% | 0 | 0 / 0 |
| skin | 40% | 27672.59 | 725 / 1809 | 16% | 103.65 | 74 / 472 |
| stomach | 45% | 32549.34 | 162 / 359 | 6% | 14.76 | 16 / 286 |
| brain | 1% | 468.68 | 31 / 2642 | 44% | 236.14 | 313 / 705 |
| pancreas | 4% | 1208.85 | 14 / 328 | 28% | 163.46 | 49 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 19.90 | 2 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 21.32 | 3 / 45 |
| peripheral blood | 0% | 118.17 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006982 | Biological process | response to lipid hydroperoxide |
| GO_0042744 | Biological process | hydrogen peroxide catabolic process |
| GO_0098869 | Biological process | cellular oxidant detoxification |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008430 | Molecular function | selenium binding |
| GO_0004602 | Molecular function | glutathione peroxidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GPX3 |
| Protein name | Glutathione peroxidase 3 (GPx-3) (GSHPx-3) (EC 1.11.1.9) (Extracellular glutathione peroxidase) (Plasma glutathione peroxidase) (GPx-P) (GSHPx-P) Glutathione peroxidase Glutathione peroxidase 3 glutathione peroxidase (EC 1.11.1.9) GPX3 protein |
| Synonyms | GPXP |
| Description | FUNCTION: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. . FUNCTION: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. . FUNCTION: Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. . |
| Accessions | A0A182DWI0 H0YC19 A0A182DWH9 E5RG32 ENST00000521650.5 ENST00000517973.1 ENST00000388825.9 ENST00000521632.1 ENST00000519214.5 Q6NXQ3 ENST00000520059.1 P22352 H0YBE4 |