GPR108 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006810Biological processtransport
GO_0034122Biological processnegative regulation of toll-like receptor signaling pathway
GO_0050776Biological processregulation of immune response
GO_0005802Cellular componenttrans-Golgi network
GO_0000139Cellular componentGolgi membrane
GO_0005794Cellular componentGolgi apparatus
GO_0033106Cellular componentcis-Golgi network membrane
GO_0016020Cellular componentmembrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGPR108
Protein nameGPR108 protein
G protein-coupled receptor 108 (HCG1811164, isoform CRA_c)
Protein GPR108 (Lung seven transmembrane receptor 2)
G protein-coupled receptor 108
SynonymshCG_1811164
LUSTR2
DescriptionFUNCTION: May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response. .; FUNCTION: (Microbial infection) Plays an essential function in adeno-associated virus (AAV) transduction across multiple serotypes except AAV5. May play a critical role in mediating the endosomal virus escape or in the AAV virions trafficking from endosomes to the nucleus. .

AccessionsENST00000430424.8
M0QYF6
ENST00000264080.12
M0R1Q3
M0R1G1
M0QZY1
M0QZW9
Q9NPR9
M0QZ03
ENST00000594500.5
ENST00000601716.1
ENST00000597706.5
ENST00000598955.1
G5E9L6
M0R2E1
Q96I30
M0R3H4
ENST00000598052.5
ENST00000597298.5
ENST00000594034.5
B9EK73
ENST00000595908.5