GNAT2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GNAT2 at tissue level.

III. Associated gene sets

GO_0097719Biological processneural tissue regeneration
GO_0007601Biological processvisual perception
GO_0048877Biological processhomeostasis of number of retina cells
GO_0007188Biological processadenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0007602Biological processphototransduction
GO_0150103Biological processreactive gliosis
GO_0060221Biological processretinal rod cell differentiation
GO_0014070Biological processresponse to organic cyclic compound
GO_0009411Biological processresponse to UV
GO_0042417Biological processdopamine metabolic process
GO_0120302Biological processbackground adaptation
GO_0048771Biological processtissue remodeling
GO_0046549Biological processretinal cone cell development
GO_0050908Biological processdetection of light stimulus involved in visual perception
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0051938Biological processL-glutamate import
GO_0010467Biological processgene expression
GO_0000902Biological processcell morphogenesis
GO_0008104Biological processprotein localization
GO_0001580Biological processdetection of chemical stimulus involved in sensory perception of bitter taste
GO_0007632Biological processvisual behavior
GO_1904390Biological processcone retinal bipolar cell differentiation
GO_0005886Cellular componentplasma membrane
GO_0001750Cellular componentphotoreceptor outer segment
GO_0001917Cellular componentphotoreceptor inner segment
GO_0042622Cellular componentphotoreceptor outer segment membrane
GO_0045202Cellular componentsynapse
GO_0005737Cellular componentcytoplasm
GO_0005834Cellular componentheterotrimeric G-protein complex
GO_0031683Molecular functionG-protein beta/gamma-subunit complex binding
GO_0008020Molecular functionG protein-coupled photoreceptor activity
GO_0001664Molecular functionG protein-coupled receptor binding
GO_0005525Molecular functionGTP binding
GO_0046872Molecular functionmetal ion binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameGNAT2
Protein nameGuanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain)
G protein subunit alpha transducin 2
SynonymshCG_40256
GNATC
DescriptionFUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

AccessionsP19087
A0A087WZE5
ENST00000622865.1
ENST00000679935.1
ENST00000351050.8
Q5T697