GLRX5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
pericyte	15 studies	27% ± 13%	Explore
erythrocyte	13 studies	45% ± 18%	Explore
smooth muscle cell	12 studies	22% ± 3%	Explore
endothelial cell	10 studies	28% ± 11%	Explore
fibroblast	9 studies	22% ± 8%	Explore
natural killer cell	7 studies	23% ± 6%	Explore
B cell	7 studies	22% ± 6%	Explore
epithelial cell	6 studies	41% ± 18%	Explore
erythroblast	5 studies	40% ± 25%	Explore
basal cell	5 studies	32% ± 13%	Explore
plasmacytoid dendritic cell	5 studies	20% ± 5%	Explore
plasmablast	4 studies	42% ± 15%	Explore
pancreatic A cell	4 studies	27% ± 3%	Explore
kidney loop of Henle epithelial cell	4 studies	22% ± 7%	Explore
endothelial cell of artery	4 studies	16% ± 0%	Explore
retinal ganglion cell	4 studies	56% ± 21%	Explore
ciliated cell	4 studies	34% ± 12%	Explore
neuron	4 studies	28% ± 15%	Explore
connective tissue cell	4 studies	23% ± 4%	Explore
leukocyte	3 studies	25% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	25% ± 8%	Explore
non-classical monocyte	3 studies	33% ± 13%	Explore
CD8-positive, alpha-beta T cell	3 studies	26% ± 9%	Explore
conventional dendritic cell	3 studies	32% ± 23%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	25% ± 7%	Explore
mature NK T cell	3 studies	20% ± 4%	Explore
transit amplifying cell	3 studies	23% ± 3%	Explore
extravillous trophoblast	3 studies	28% ± 15%	Explore
myofibroblast cell	3 studies	21% ± 5%	Explore
myeloid cell	3 studies	25% ± 7%	Explore
neuroendocrine cell	3 studies	32% ± 9%	Explore
pro-B cell	3 studies	19% ± 0%	Explore
retinal cone cell	3 studies	33% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	27% ± 5%	Explore
mesothelial cell	3 studies	28% ± 15%	Explore
pancreatic ductal cell	3 studies	41% ± 4%	Explore
abnormal cell	3 studies	28% ± 6%	Explore
goblet cell	3 studies	25% ± 8%	Explore
endothelial cell of vascular tree	3 studies	17% ± 2%	Explore
hepatocyte	3 studies	39% ± 30%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	5 studies	26% ± 14%	Explore
intestine	5 studies	22% ± 9%	Explore
pancreas	4 studies	28% ± 6%	Explore
peripheral blood	4 studies	31% ± 10%	Explore
liver	4 studies	36% ± 29%	Explore
breast	3 studies	18% ± 2%	Explore
brain	3 studies	22% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1745.54	1445 / 1445	100%	49.60	183 / 183
liver	100%	2692.30	226 / 226	100%	80.48	406 / 406
ovary	100%	2055.59	180 / 180	100%	91.74	430 / 430
stomach	100%	1685.83	359 / 359	100%	57.01	286 / 286
thymus	100%	1792.02	653 / 653	100%	61.64	605 / 605
uterus	100%	1473.27	170 / 170	100%	70.87	459 / 459
brain	100%	2147.41	2640 / 2642	100%	60.80	705 / 705
skin	100%	1754.38	1807 / 1809	100%	55.03	472 / 472
intestine	100%	2237.07	966 / 966	100%	59.43	526 / 527
bladder	100%	1934.67	21 / 21	100%	62.18	503 / 504
kidney	100%	3138.28	89 / 89	100%	50.55	899 / 901
adrenal gland	100%	3882.99	258 / 258	100%	71.25	229 / 230
breast	100%	1984.37	459 / 459	100%	71.00	1113 / 1118
pancreas	99%	1020.16	326 / 328	100%	51.75	178 / 178
lung	99%	1474.20	574 / 578	100%	57.43	1155 / 1155
prostate	100%	1567.13	244 / 245	100%	64.39	500 / 502
adipose	100%	1853.25	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	60.34	80 / 80
lymph node	0%	0	0 / 0	100%	70.26	29 / 29
muscle	100%	3788.06	803 / 803	0%	0	0 / 0
spleen	100%	1754.20	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	58.93	45 / 45
ureter	0%	0	0 / 0	100%	54.48	1 / 1
peripheral blood	100%	2998.92	928 / 929	0%	0	0 / 0
blood vessel	100%	1800.81	1333 / 1335	0%	0	0 / 0
heart	99%	3109.66	852 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045454	Biological process	cell redox homeostasis
GO_0016226	Biological process	iron-sulfur cluster assembly
GO_0106035	Biological process	protein maturation by [4Fe-4S] cluster transfer
GO_0030097	Biological process	hemopoiesis
GO_0006879	Biological process	intracellular iron ion homeostasis
GO_0106034	Biological process	protein maturation by [2Fe-2S] cluster transfer
GO_0044571	Biological process	[2Fe-2S] cluster assembly
GO_1990229	Cellular component	iron-sulfur cluster assembly complex
GO_0043025	Cellular component	neuronal cell body
GO_0005759	Cellular component	mitochondrial matrix
GO_0005739	Cellular component	mitochondrion
GO_0030425	Cellular component	dendrite
GO_0051537	Molecular function	2 iron, 2 sulfur cluster binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	GLRX5
Protein name	Glutaredoxin 5 Glutaredoxin 5 homolog (S. cerevisiae), isoform CRA_a (PRO1238) Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5)
Synonyms	hCG_24440 C14orf87
Description	FUNCTION: Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer . Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion . Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 . .
Accessions	ENST00000557731.1 ENST00000331334.5 H0YJM6 Q9P1N5 Q86SX6

GLRX5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review