GLRA3 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	6 studies	38% ± 19%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	36% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	76%	438.18	2018 / 2642	58%	4.01	412 / 705
breast	45%	709.35	205 / 459	23%	4.51	252 / 1118
adrenal gland	21%	33.04	55 / 258	19%	1.61	44 / 230
lymph node	0%	0	0 / 0	28%	1.30	8 / 29
pancreas	11%	6.09	37 / 328	8%	0.23	14 / 178
esophagus	12%	13.06	167 / 1445	4%	0.08	7 / 183
lung	1%	0.39	4 / 578	8%	0.35	93 / 1155
intestine	7%	8.18	71 / 966	1%	0.02	5 / 527
uterus	7%	7.25	12 / 170	1%	0.05	5 / 459
spleen	6%	2.95	14 / 241	0%	0	0 / 0
bladder	0%	0	0 / 21	5%	0.12	23 / 504
kidney	3%	1.75	3 / 89	0%	0.01	3 / 901
thymus	0%	0.21	3 / 653	2%	0.03	10 / 605
stomach	0%	0.16	1 / 359	2%	0.09	5 / 286
skin	2%	0.95	29 / 1809	0%	0.00	1 / 472
prostate	0%	0	0 / 245	1%	0.31	6 / 502
adipose	1%	0.64	13 / 1204	0%	0	0 / 0
blood vessel	0%	0.45	5 / 1335	0%	0	0 / 0
ovary	0%	0	0 / 180	0%	0.00	1 / 430
heart	0%	0.21	2 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
liver	0%	0	0 / 226	0%	0	0 / 406
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051260	Biological process	protein homooligomerization
GO_0042391	Biological process	regulation of membrane potential
GO_0060079	Biological process	excitatory postsynaptic potential
GO_1902476	Biological process	chloride transmembrane transport
GO_0007268	Biological process	chemical synaptic transmission
GO_0005886	Cellular component	plasma membrane
GO_0043204	Cellular component	perikaryon
GO_1902495	Cellular component	transmembrane transporter complex
GO_0043005	Cellular component	neuron projection
GO_0030425	Cellular component	dendrite
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0016935	Cellular component	glycine-gated chloride channel complex
GO_0004888	Molecular function	transmembrane signaling receptor activity
GO_0005231	Molecular function	excitatory extracellular ligand-gated monoatomic ion channel activity
GO_0016934	Molecular function	extracellularly glycine-gated chloride channel activity
GO_0030594	Molecular function	neurotransmitter receptor activity
GO_0046872	Molecular function	metal ion binding
GO_0016594	Molecular function	glycine binding
GO_0022852	Molecular function	glycine-gated chloride ion channel activity
GO_0005254	Molecular function	chloride channel activity

Gene name	GLRA3
Protein name	Glycine receptor subunit alpha-3 Uncharacterized protein GLRA3 Glycine receptor alpha 3 subunit
Synonyms
Description	FUNCTION: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine . Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity). Plays an important role in the down-regulation of neuronal excitability (By similarity). Contributes to the generation of inhibitory postsynaptic currents (By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity). Plays a role in cellular responses to ethanol (By similarity). .
Accessions	Q4W595 ENST00000274093.8 [O75311-1] O75311 Q9UPF3 ENST00000340217.5 [O75311-2]

GLRA3 report