GFM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070125Biological processmitochondrial translational elongation
GO_0005739Cellular componentmitochondrion
GO_0005759Cellular componentmitochondrial matrix
GO_0005525Molecular functionGTP binding
GO_0003924Molecular functionGTPase activity
GO_0003746Molecular functiontranslation elongation factor activity
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameGFM1
Protein nameElongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1)
G elongation factor mitochondrial 1 isoform 3
Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1)
G elongation factor mitochondrial 1
SynonymsEFG
EFG1
GFM
DescriptionFUNCTION: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. .

FUNCTION: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. .

FUNCTION: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. .

AccessionsENST00000264263.9 [Q96RP9-2]
A0A0S2Z5W5
F8WAU4
C9IZ01
E5KND5
E5KND7
ENST00000478576.5
C9JA25
Q96RP9
ENST00000486715.6 [Q96RP9-1]
ENST00000478254.5
ENST00000472383.1
ENST00000464732.1
H7C5M4