Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 33% ± 9% | |
| enterocyte | 4 studies | 33% ± 7% | |
| non-classical monocyte | 3 studies | 21% ± 4% | |
| ciliated cell | 3 studies | 28% ± 3% | |
| macrophage | 3 studies | 17% ± 2% | |
| dendritic cell | 3 studies | 26% ± 4% | |
| natural killer cell | 3 studies | 18% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 693.75 | 1445 / 1445 | 100% | 7.38 | 183 / 183 |
| ovary | 100% | 447.92 | 180 / 180 | 100% | 11.50 | 430 / 430 |
| pancreas | 100% | 742.76 | 328 / 328 | 100% | 9.76 | 178 / 178 |
| thymus | 100% | 739.34 | 653 / 653 | 100% | 10.71 | 605 / 605 |
| brain | 100% | 888.21 | 2641 / 2642 | 100% | 14.86 | 705 / 705 |
| uterus | 100% | 687.73 | 170 / 170 | 100% | 10.86 | 457 / 459 |
| liver | 100% | 722.71 | 226 / 226 | 100% | 8.26 | 404 / 406 |
| intestine | 100% | 1115.20 | 966 / 966 | 99% | 12.81 | 524 / 527 |
| prostate | 100% | 883.15 | 245 / 245 | 99% | 10.42 | 499 / 502 |
| stomach | 100% | 656.80 | 359 / 359 | 99% | 11.82 | 284 / 286 |
| skin | 100% | 602.03 | 1809 / 1809 | 99% | 8.81 | 468 / 472 |
| kidney | 100% | 800.30 | 89 / 89 | 99% | 9.17 | 890 / 901 |
| adrenal gland | 100% | 693.85 | 258 / 258 | 99% | 10.86 | 227 / 230 |
| bladder | 100% | 800.71 | 21 / 21 | 98% | 9.75 | 496 / 504 |
| breast | 100% | 650.03 | 459 / 459 | 97% | 10.21 | 1088 / 1118 |
| lung | 100% | 625.26 | 576 / 578 | 97% | 7.30 | 1124 / 1155 |
| adipose | 100% | 595.34 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 599.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 10.23 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 11.94 | 29 / 29 |
| spleen | 100% | 798.94 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 8.22 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.81 | 1 / 1 |
| heart | 100% | 500.13 | 859 / 861 | 0% | 0 | 0 / 0 |
| muscle | 100% | 608.40 | 801 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 90% | 384.81 | 834 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0072717 | Biological process | cellular response to actinomycin D |
| GO_0007165 | Biological process | signal transduction |
| GO_0001889 | Biological process | liver development |
| GO_0071356 | Biological process | cellular response to tumor necrosis factor |
| GO_0045953 | Biological process | negative regulation of natural killer cell mediated cytotoxicity |
| GO_0097421 | Biological process | liver regeneration |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_2000573 | Biological process | positive regulation of DNA biosynthetic process |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0097237 | Biological process | cellular response to toxic substance |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005758 | Cellular component | mitochondrial intermembrane space |
| GO_0005829 | Cellular component | cytosol |
| GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
| GO_0015035 | Molecular function | protein-disulfide reductase activity |
| GO_0016971 | Molecular function | flavin-dependent sulfhydryl oxidase activity |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GFER |
| Protein name | FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin) Growth factor, augmenter of liver regeneration Sulfhydryl oxidase (EC 1.8.3.2) |
| Synonyms | HERV1 ALR HPO hCG_42694 |
| Description | FUNCTION: [Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. .; FUNCTION: [Isoform 2]: May act as an autocrine hepatotrophic growth factor promoting liver regeneration. |
| Accessions | ENST00000248114.7 [P55789-1] H3BRW3 H3BRD2 ENST00000561710.1 ENST00000569451.1 P55789 H3BQQ4 ENST00000709288.1 [P55789-1] ENST00000567719.2 |
