GDPD5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007399Biological processnervous system development
GO_0045666Biological processpositive regulation of neuron differentiation
GO_0006629Biological processlipid metabolic process
GO_0005886Cellular componentplasma membrane
GO_0030426Cellular componentgrowth cone
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0012505Cellular componentendomembrane system
GO_0008889Molecular functionglycerophosphodiester phosphodiesterase activity
GO_0047389Molecular functionglycerophosphocholine phosphodiesterase activity
GO_0005515Molecular functionprotein binding
GO_0004435Molecular functionphosphatidylinositol phospholipase C activity

IV. Literature review

[source]
Gene nameGDPD5
Protein nameGDPD5 protein
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (Glycerophosphocholine phosphodiesterase GDPD5) (EC 3.1.4.2) (Glycerophosphodiester phosphodiesterase 2) (Phosphoinositide phospholipase C GDPD5) (EC 3.1.4.11)
Glycerophosphodiester phosphodiesterase domain containing 5
SynonymsPP9363
GDE2
PP6037
UNQ1850/PRO3580
DKFZp434D0316
DescriptionFUNCTION: Glycerophosphodiester phosphodiesterase that promotes neurite formation and drives spinal motor neuron differentiation (By similarity). Mediates the cleavage of glycosylphosphatidylinositol (GPI) anchor of target proteins: removes the GPI-anchor of RECK, leading to release RECK from the plasma membrane (By similarity). May contribute to the osmotic regulation of cellular glycerophosphocholine (By similarity). .

AccessionsH0YEF5
ENST00000533805.5 [Q8WTR4-5]
ENST00000534322.1
E9PJU5
ENST00000533784.5 [Q8WTR4-2]
ENST00000532435.5
ENST00000527820.5
ENST00000526177.5 [Q8WTR4-3]
ENST00000336898.8 [Q8WTR4-1]
Q8NDN3
ENST00000529721.5 [Q8WTR4-1]
Q8WTR4
ENST00000443276.6
Q9HBR3