Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 17 studies | 50% ± 21% | |
| oligodendrocyte | 14 studies | 42% ± 15% | |
| glutamatergic neuron | 11 studies | 41% ± 20% | |
| microglial cell | 9 studies | 39% ± 12% | |
| GABAergic neuron | 8 studies | 42% ± 22% | |
| adipocyte | 8 studies | 36% ± 10% | |
| fibroblast | 8 studies | 21% ± 4% | |
| endothelial cell | 6 studies | 27% ± 7% | |
| epithelial cell | 6 studies | 29% ± 19% | |
| type II pneumocyte | 6 studies | 37% ± 12% | |
| cardiac muscle cell | 5 studies | 37% ± 9% | |
| club cell | 5 studies | 31% ± 14% | |
| hepatocyte | 4 studies | 46% ± 31% | |
| neuron | 4 studies | 32% ± 20% | |
| ciliated cell | 4 studies | 22% ± 7% | |
| Mueller cell | 4 studies | 45% ± 7% | |
| basal cell | 4 studies | 26% ± 12% | |
| smooth muscle cell | 4 studies | 22% ± 3% | |
| interneuron | 4 studies | 52% ± 20% | |
| oligodendrocyte precursor cell | 4 studies | 30% ± 10% | |
| ON-bipolar cell | 3 studies | 35% ± 15% | |
| retina horizontal cell | 3 studies | 27% ± 8% | |
| rod bipolar cell | 3 studies | 36% ± 14% | |
| cholangiocyte | 3 studies | 49% ± 29% | |
| ependymal cell | 3 studies | 37% ± 28% | |
| respiratory goblet cell | 3 studies | 35% ± 15% | |
| goblet cell | 3 studies | 38% ± 28% | |
| granule cell | 3 studies | 31% ± 5% | |
| pericyte | 3 studies | 22% ± 3% | |
| mucus secreting cell | 3 studies | 31% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1140.95 | 1444 / 1445 | 99% | 15.37 | 182 / 183 |
| brain | 100% | 1131.05 | 2629 / 2642 | 99% | 10.50 | 695 / 705 |
| kidney | 100% | 1646.74 | 89 / 89 | 98% | 20.57 | 881 / 901 |
| pancreas | 100% | 1782.29 | 328 / 328 | 98% | 9.28 | 174 / 178 |
| stomach | 100% | 1059.68 | 359 / 359 | 97% | 8.34 | 276 / 286 |
| bladder | 100% | 1105.43 | 21 / 21 | 96% | 13.05 | 484 / 504 |
| intestine | 99% | 887.79 | 958 / 966 | 97% | 7.19 | 509 / 527 |
| ovary | 98% | 571.28 | 176 / 180 | 96% | 6.67 | 412 / 430 |
| lung | 96% | 716.84 | 554 / 578 | 97% | 10.18 | 1126 / 1155 |
| prostate | 100% | 830.67 | 245 / 245 | 91% | 5.85 | 458 / 502 |
| uterus | 97% | 532.98 | 165 / 170 | 92% | 9.73 | 422 / 459 |
| breast | 100% | 1134.80 | 458 / 459 | 83% | 6.32 | 933 / 1118 |
| skin | 95% | 1919.19 | 1720 / 1809 | 77% | 6.49 | 363 / 472 |
| liver | 100% | 941.77 | 225 / 226 | 67% | 4.43 | 274 / 406 |
| adrenal gland | 100% | 1626.28 | 258 / 258 | 61% | 3.21 | 140 / 230 |
| thymus | 92% | 376.39 | 603 / 653 | 68% | 3.17 | 409 / 605 |
| adipose | 100% | 1104.53 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.18 | 1 / 1 |
| blood vessel | 99% | 1335.04 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 823.13 | 793 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 10.62 | 42 / 45 |
| heart | 92% | 700.09 | 796 / 861 | 0% | 0 | 0 / 0 |
| spleen | 71% | 315.17 | 171 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 44% | 1.60 | 35 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.19 | 2 / 29 |
| peripheral blood | 1% | 2.04 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0051781 | Biological process | positive regulation of cell division |
| GO_0070374 | Biological process | positive regulation of ERK1 and ERK2 cascade |
| GO_0071364 | Biological process | cellular response to epidermal growth factor stimulus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0070064 | Molecular function | proline-rich region binding |
| Gene name | GAREM1 |
| Protein name | GRB2 associated regulator of MAPK1 subtype 1 GRB2-associated and regulator of MAPK protein 1 (GRB2-associated and regulator of MAPK1) |
| Synonyms | FAM59A GAREM C18orf11 |
| Description | FUNCTION: [Isoform 1]: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation. . |
| Accessions | ENST00000399218.8 [Q9H706-3] ENST00000269209.7 [Q9H706-1] J3QRF3 ENST00000583696.1 Q9H706 |