GAREM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007173Biological processepidermal growth factor receptor signaling pathway
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0051781Biological processpositive regulation of cell division
GO_0070374Biological processpositive regulation of ERK1 and ERK2 cascade
GO_0071364Biological processcellular response to epidermal growth factor stimulus
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding
GO_0070064Molecular functionproline-rich region binding

IV. Literature review

[source]
Gene nameGAREM1
Protein nameGRB2 associated regulator of MAPK1 subtype 1
GRB2-associated and regulator of MAPK protein 1 (GRB2-associated and regulator of MAPK1)
SynonymsFAM59A
GAREM
C18orf11
DescriptionFUNCTION: [Isoform 1]: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation. .

AccessionsENST00000399218.8 [Q9H706-3]
ENST00000269209.7 [Q9H706-1]
J3QRF3
ENST00000583696.1
Q9H706