FRY report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1904428Biological processnegative regulation of tubulin deacetylation
GO_0000902Biological processcell morphogenesis
GO_0031175Biological processneuron projection development
GO_0005813Cellular componentcentrosome
GO_0005938Cellular componentcell cortex
GO_0000922Cellular componentspindle pole
GO_0030427Cellular componentsite of polarized growth
GO_0004857Molecular functionenzyme inhibitor activity

IV. Literature review

[source]
Gene nameFRY
Protein nameAlternative protein FRY
FRY microtubule binding protein
Protein furry homolog
SynonymsC13orf14
DescriptionFUNCTION: Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation. .

AccessionsENST00000542859.6
Q5TBA9
H0YE00
A0A2R8Y5V8
A0A2R8YCY2
ENST00000647500.1
ENST00000642040.1
A0A2R8Y7Y8
A0A286YFA9
ENST00000645780.1
ENST00000436046.1
ENST00000477712.2
ENST00000643293.1
B1ALA1
L8EB55