FREM1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
fibroblast	8 studies	24% ± 8%	Explore
mast cell	5 studies	22% ± 5%	Explore
GABAergic neuron	5 studies	35% ± 12%	Explore
adipocyte	4 studies	35% ± 9%	Explore
renal beta-intercalated cell	3 studies	45% ± 19%	Explore
GABAergic interneuron	3 studies	17% ± 2%	Explore
glutamatergic neuron	3 studies	38% ± 11%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	35% ± 16%	Explore
astrocyte	3 studies	34% ± 14%	Explore
interneuron	3 studies	34% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	5 studies	25% ± 7%	Explore
kidney	3 studies	27% ± 6%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	99%	1235.40	325 / 328	70%	3.13	125 / 178
intestine	92%	1493.73	884 / 966	59%	6.53	313 / 527
kidney	100%	2107.70	89 / 89	51%	2.74	457 / 901
brain	62%	683.12	1648 / 2642	72%	3.34	511 / 705
lung	90%	652.43	518 / 578	43%	1.36	496 / 1155
breast	87%	727.56	399 / 459	45%	1.42	498 / 1118
uterus	99%	2900.75	168 / 170	31%	2.60	144 / 459
bladder	81%	560.71	17 / 21	46%	2.48	232 / 504
skin	56%	278.44	1020 / 1809	44%	8.18	209 / 472
adrenal gland	87%	508.11	224 / 258	13%	0.34	30 / 230
blood vessel	99%	1958.72	1320 / 1335	0%	0	0 / 0
prostate	58%	244.87	142 / 245	40%	0.77	200 / 502
stomach	35%	209.55	127 / 359	61%	5.09	175 / 286
ovary	65%	419.27	117 / 180	31%	1.25	135 / 430
adipose	91%	662.67	1094 / 1204	0%	0	0 / 0
heart	80%	755.75	685 / 861	0%	0	0 / 0
esophagus	44%	244.78	630 / 1445	28%	1.25	51 / 183
thymus	47%	186.96	304 / 653	12%	0.54	72 / 605
muscle	19%	60.45	152 / 803	0%	0	0 / 0
liver	8%	20.58	17 / 226	9%	0.60	35 / 406
lymph node	0%	0	0 / 0	14%	0.20	4 / 29
spleen	14%	54.83	33 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	9%	0.10	4 / 45
peripheral blood	0%	2.17	3 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1