FGD6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046847Biological processfilopodium assembly
GO_0008360Biological processregulation of cell shape
GO_0030036Biological processactin cytoskeleton organization
GO_0043087Biological processregulation of GTPase activity
GO_0007010Biological processcytoskeleton organization
GO_0001726Cellular componentruffle
GO_0005856Cellular componentcytoskeleton
GO_0030027Cellular componentlamellipodium
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0031267Molecular functionsmall GTPase binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameFGD6
Protein nameFYVE, RhoGEF and PH domain containing 6
FGD6
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
FGD6 protein
SynonymsZFYVE24
KIAA1362
DescriptionFUNCTION: May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity). .

AccessionsH0YI21
ENST00000451107.3
ENST00000546711.5 [Q6ZV73-2]
F8VWT6
ENST00000549499.1
F8VQX5
F8VY01
A4FVC4
A0A2X0SFJ2
ENST00000551521.5
Q6ZV73
ENST00000548069.5
ENST00000343958.9 [Q6ZV73-1]