FASTKD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0044528Biological processregulation of mitochondrial mRNA stability
GO_0006915Biological processapoptotic process
GO_0070131Biological processpositive regulation of mitochondrial translation
GO_0032543Biological processmitochondrial translation
GO_0000963Biological processmitochondrial RNA processing
GO_1902775Biological processmitochondrial large ribosomal subunit assembly
GO_0006396Biological processRNA processing
GO_0035770Cellular componentribonucleoprotein granule
GO_0005739Cellular componentmitochondrion
GO_0005759Cellular componentmitochondrial matrix
GO_0042645Cellular componentmitochondrial nucleoid
GO_0019843Molecular functionrRNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameFASTKD2
Protein nameFAST kinase domain-containing protein 2, mitochondrial
FAST kinase domains 2
SynonymsKIAA0971
DescriptionFUNCTION: Plays an important role in assembly of the mitochondrial large ribosomal subunit . As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation . May play a role in mitochondrial apoptosis. .

AccessionsENST00000236980.10 [Q9NYY8-1]
Q9NYY8
C9JPI6
ENST00000418289.1
ENST00000402774.8 [Q9NYY8-1]
ENST00000403094.3 [Q9NYY8-1]