Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 28% ± 9% | |
oligodendrocyte precursor cell | 11 studies | 35% ± 15% | |
oligodendrocyte | 10 studies | 33% ± 12% | |
epithelial cell | 6 studies | 29% ± 16% | |
fibroblast | 6 studies | 20% ± 4% | |
glutamatergic neuron | 5 studies | 40% ± 20% | |
microglial cell | 5 studies | 25% ± 5% | |
adipocyte | 5 studies | 19% ± 3% | |
ciliated cell | 5 studies | 26% ± 9% | |
goblet cell | 5 studies | 37% ± 24% | |
macrophage | 5 studies | 27% ± 13% | |
pericyte | 5 studies | 21% ± 5% | |
interneuron | 4 studies | 34% ± 21% | |
neuron | 4 studies | 35% ± 17% | |
astrocyte | 4 studies | 34% ± 8% | |
dendritic cell | 4 studies | 22% ± 1% | |
endothelial cell of lymphatic vessel | 4 studies | 21% ± 4% | |
type I pneumocyte | 4 studies | 20% ± 5% | |
mast cell | 3 studies | 19% ± 2% | |
hepatocyte | 3 studies | 33% ± 11% | |
GABAergic neuron | 3 studies | 47% ± 7% | |
brush cell | 3 studies | 30% ± 4% | |
smooth muscle cell | 3 studies | 18% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 34% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1749.70 | 1445 / 1445 | 100% | 17.09 | 183 / 183 |
stomach | 100% | 1742.48 | 359 / 359 | 100% | 16.16 | 286 / 286 |
intestine | 100% | 2400.51 | 966 / 966 | 100% | 15.61 | 526 / 527 |
lung | 100% | 1887.17 | 577 / 578 | 100% | 10.10 | 1153 / 1155 |
skin | 100% | 3315.60 | 1809 / 1809 | 99% | 39.75 | 469 / 472 |
breast | 100% | 1654.53 | 459 / 459 | 99% | 10.05 | 1106 / 1118 |
pancreas | 100% | 1078.77 | 327 / 328 | 99% | 10.85 | 176 / 178 |
bladder | 100% | 1819.48 | 21 / 21 | 98% | 9.02 | 494 / 504 |
prostate | 100% | 1603.56 | 245 / 245 | 98% | 7.64 | 492 / 502 |
ovary | 100% | 1783.32 | 180 / 180 | 97% | 6.93 | 419 / 430 |
brain | 98% | 1268.61 | 2585 / 2642 | 100% | 7.97 | 702 / 705 |
uterus | 100% | 1814.88 | 170 / 170 | 96% | 7.59 | 441 / 459 |
kidney | 100% | 1457.96 | 89 / 89 | 91% | 5.47 | 824 / 901 |
adrenal gland | 100% | 1576.60 | 258 / 258 | 83% | 4.55 | 191 / 230 |
thymus | 100% | 1295.35 | 652 / 653 | 75% | 3.08 | 453 / 605 |
liver | 100% | 1031.16 | 226 / 226 | 70% | 3.14 | 285 / 406 |
adipose | 100% | 1692.14 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1836.00 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1746.67 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.16 | 1 / 1 |
muscle | 99% | 942.66 | 798 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 14.60 | 79 / 80 |
tonsil | 0% | 0 | 0 / 0 | 98% | 9.03 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 97% | 8.27 | 28 / 29 |
heart | 94% | 850.36 | 811 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 34% | 829.51 | 315 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071800 | Biological process | podosome assembly |
GO_0033623 | Biological process | regulation of integrin activation |
GO_0022405 | Biological process | hair cycle process |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0071526 | Biological process | semaphorin-plexin signaling pathway |
GO_0007155 | Biological process | cell adhesion |
GO_0016322 | Biological process | neuron remodeling |
GO_0016601 | Biological process | Rac protein signal transduction |
GO_0030316 | Biological process | osteoclast differentiation |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0008092 | Molecular function | cytoskeletal protein binding |
Gene name | FARP2 |
Protein name | FERM, ARH/RhoGEF and pleckstrin domain protein 2 FARP2 FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3) |
Synonyms | PLEKHC3 KIAA0793 |
Description | FUNCTION: Functions as a guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). . |
Accessions | ENST00000373287.8 [O94887-2] O94887 ENST00000445489.1 ENST00000418082.1 H7C210 C9JWM9 H7C3M7 ENST00000444371.1 A0A2X0SSL3 ENST00000264042.8 [O94887-1] ENST00000422951.1 ENST00000413432.2 H7C447 C9JVQ5 H7C3E4 ENST00000627550.2 [O94887-3] ENST00000412332.1 |