Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 13 studies | 38% ± 15% | |
endothelial cell | 11 studies | 26% ± 8% | |
oligodendrocyte precursor cell | 9 studies | 31% ± 16% | |
neuron | 5 studies | 35% ± 16% | |
glutamatergic neuron | 5 studies | 49% ± 27% | |
GABAergic neuron | 4 studies | 44% ± 17% | |
fibroblast | 4 studies | 22% ± 7% | |
epithelial cell | 4 studies | 26% ± 8% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 4% | |
astrocyte | 4 studies | 32% ± 8% | |
interneuron | 4 studies | 39% ± 21% | |
microglial cell | 3 studies | 19% ± 1% | |
hepatocyte | 3 studies | 30% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 407.11 | 1444 / 1445 | 100% | 19.23 | 183 / 183 |
breast | 100% | 533.91 | 459 / 459 | 100% | 26.01 | 1116 / 1118 |
prostate | 100% | 635.40 | 245 / 245 | 100% | 16.55 | 501 / 502 |
brain | 100% | 650.79 | 2637 / 2642 | 100% | 18.95 | 704 / 705 |
ovary | 100% | 793.57 | 180 / 180 | 100% | 15.61 | 428 / 430 |
bladder | 100% | 515.57 | 21 / 21 | 99% | 21.49 | 501 / 504 |
uterus | 100% | 817.68 | 170 / 170 | 99% | 28.41 | 456 / 459 |
thymus | 100% | 741.35 | 653 / 653 | 99% | 21.16 | 600 / 605 |
adrenal gland | 100% | 1486.57 | 258 / 258 | 99% | 25.61 | 228 / 230 |
intestine | 100% | 526.25 | 966 / 966 | 99% | 18.13 | 522 / 527 |
stomach | 100% | 359.51 | 358 / 359 | 99% | 16.75 | 284 / 286 |
pancreas | 100% | 382.68 | 327 / 328 | 99% | 17.36 | 176 / 178 |
lung | 99% | 412.01 | 570 / 578 | 100% | 21.11 | 1154 / 1155 |
skin | 99% | 418.47 | 1792 / 1809 | 97% | 26.31 | 458 / 472 |
kidney | 100% | 378.64 | 89 / 89 | 94% | 12.68 | 851 / 901 |
liver | 99% | 429.38 | 224 / 226 | 90% | 9.47 | 366 / 406 |
lymph node | 0% | 0 | 0 / 0 | 100% | 15.94 | 29 / 29 |
spleen | 100% | 692.33 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 30.00 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.79 | 1 / 1 |
adipose | 100% | 417.70 | 1201 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 369.30 | 1330 / 1335 | 0% | 0 | 0 / 0 |
heart | 95% | 255.28 | 818 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 18.08 | 75 / 80 |
muscle | 87% | 175.75 | 697 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 23% | 370.86 | 211 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006281 | Biological process | DNA repair |
GO_0036297 | Biological process | interstrand cross-link repair |
GO_0006974 | Biological process | DNA damage response |
GO_0007276 | Biological process | gamete generation |
GO_0006513 | Biological process | protein monoubiquitination |
GO_0042127 | Biological process | regulation of cell population proliferation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005635 | Cellular component | nuclear envelope |
GO_0043240 | Cellular component | Fanconi anaemia nuclear complex |
GO_0016604 | Cellular component | nuclear body |
GO_0005829 | Cellular component | cytosol |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | FANCL |
Protein name | FA complementation group L (Fanconi anemia, complementation group L, isoform CRA_e) FA complementation group L E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL) FA complementation group L (cDNA FLJ51649, highly similar to Ubiquitin ligase protein FANCL) |
Synonyms | hCG_15202 PHF9 |
Description | FUNCTION: Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway . Also mediates monoubiquitination of FANCI . May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. . |
Accessions | ENST00000696620.1 A0A8Q3WL81 ENST00000696326.1 A0A8Q3WM82 A0A8Q3WLF5 ENST00000696371.1 ENST00000696469.1 A0A8Q3WL92 A0A8Q3WMB2 H7C1M0 ENST00000696528.1 A0A8Q3SJE4 ENST00000696415.1 ENST00000696317.1 A0A8Q3WLA2 A0A8Q3WLC1 ENST00000696546.1 A0A8Q3WLH7 ENST00000696594.1 ENST00000696374.1 ENST00000696315.1 ENST00000696342.1 A0A8Q3SIV2 ENST00000696344.1 ENST00000696634.1 A0A8Q3SIK6 ENST00000446381.6 A0A8Q3WM87 A0A8Q3WL96 ENST00000696472.1 ENST00000233741.9 [Q9NW38-1] ENST00000696492.1 A0A8Q3SIV1 ENST00000696527.1 ENST00000403295.8 ENST00000696550.1 ENST00000696455.1 A0A8Q3WMB7 ENST00000696545.1 ENST00000449070.6 A0A8Q3SIE7 ENST00000696307.1 A0A8Q3SIM8 A0A8Q3WLU8 ENST00000696570.1 ENST00000696567.1 ENST00000696493.1 C9JZA9 A0A8Q3WLC2 A0A8Q3SIK9 A0A8Q3SIR8 ENST00000696598.1 ENST00000696319.1 ENST00000696308.1 ENST00000696362.1 ENST00000696499.1 ENST00000696511.1 ENST00000696361.1 ENST00000696373.1 ENST00000481670.3 ENST00000696379.1 A0A8Q3WMD8 ENST00000696435.1 ENST00000696418.1 ENST00000696476.1 ENST00000696467.1 A0A8Q3WMF8 A0A8Q3SIL3 ENST00000696495.1 ENST00000696306.1 ENST00000696508.1 ENST00000403676.6 A0A087X0C0 ENST00000696454.1 A0A8Q3WMF1 ENST00000696596.1 ENST00000696438.1 ENST00000427708.7 A0A8Q3WLB8 ENST00000696314.1 A0A8Q3SIH3 ENST00000696595.1 A0A8Q3WLA4 ENST00000696417.1 ENST00000696565.1 A0A8Q3WMD3 Q9NW38 A0A8Q3WLD6 ENST00000696459.1 ENST00000696530.1 ENST00000696461.1 ENST00000696543.1 A0A8Q3WLA5 ENST00000696458.1 A0A8Q3SIP2 A0A8Q3SIH1 ENST00000696548.1 ENST00000696324.1 ENST00000402135.8 [Q9NW38-2] A0A8Q3WLB5 C9J512 B5MC31 ENST00000696403.1 ENST00000696321.1 ENST00000696531.1 A0A8Q3SIS2 ENST00000696551.1 ENST00000417361.2 ENST00000696468.1 ENST00000696433.1 ENST00000696549.1 ENST00000696473.1 ENST00000696624.1 A0A8Q3WLA7 A0A8Q3SIM1 B5MCZ6 ENST00000696410.1 ENST00000696400.1 ENST00000696510.1 ENST00000696398.1 ENST00000696478.1 A0A8Q3WLW1 ENST00000696318.1 A0A8Q3SIX5 A0A8Q3WL94 ENST00000696457.1 A0A8Q3WMH1 ENST00000696564.1 A0A8Q3WM99 ENST00000696635.1 A0A8Q3SIS7 A0A8Q3WLF1 ENST00000696625.1 ENST00000696409.1 ENST00000696316.1 A0A8Q3WL63 A0A8Q3WL68 ENST00000696347.1 ENST00000696305.1 ENST00000696547.1 ENST00000696621.1 ENST00000696378.1 ENST00000696597.1 A0A8Q3SIP3 A0A8Q3SIQ9 A0A8Q3WLE2 A0A8Q3WL86 ENST00000696544.1 A0A8Q3SIK5 A0A8Q3SIQ5 A0A8Q3SIR9 B4DN24 ENST00000696509.1 ENST00000696434.1 |