FANCL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006281Biological processDNA repair
GO_0036297Biological processinterstrand cross-link repair
GO_0006974Biological processDNA damage response
GO_0007276Biological processgamete generation
GO_0006513Biological processprotein monoubiquitination
GO_0042127Biological processregulation of cell population proliferation
GO_0005654Cellular componentnucleoplasm
GO_0005635Cellular componentnuclear envelope
GO_0043240Cellular componentFanconi anaemia nuclear complex
GO_0016604Cellular componentnuclear body
GO_0005829Cellular componentcytosol
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0046872Molecular functionmetal ion binding
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFANCL
Protein nameFA complementation group L (Fanconi anemia, complementation group L, isoform CRA_e)
FA complementation group L
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL)
FA complementation group L (cDNA FLJ51649, highly similar to Ubiquitin ligase protein FANCL)
SynonymshCG_15202
PHF9
DescriptionFUNCTION: Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway . Also mediates monoubiquitination of FANCI . May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. .

AccessionsENST00000696620.1
A0A8Q3WL81
ENST00000696326.1
A0A8Q3WM82
A0A8Q3WLF5
ENST00000696371.1
ENST00000696469.1
A0A8Q3WL92
A0A8Q3WMB2
H7C1M0
ENST00000696528.1
A0A8Q3SJE4
ENST00000696415.1
ENST00000696317.1
A0A8Q3WLA2
A0A8Q3WLC1
ENST00000696546.1
A0A8Q3WLH7
ENST00000696594.1
ENST00000696374.1
ENST00000696315.1
ENST00000696342.1
A0A8Q3SIV2
ENST00000696344.1
ENST00000696634.1
A0A8Q3SIK6
ENST00000446381.6
A0A8Q3WM87
A0A8Q3WL96
ENST00000696472.1
ENST00000233741.9 [Q9NW38-1]
ENST00000696492.1
A0A8Q3SIV1
ENST00000696527.1
ENST00000403295.8
ENST00000696550.1
ENST00000696455.1
A0A8Q3WMB7
ENST00000696545.1
ENST00000449070.6
A0A8Q3SIE7
ENST00000696307.1
A0A8Q3SIM8
A0A8Q3WLU8
ENST00000696570.1
ENST00000696567.1
ENST00000696493.1
C9JZA9
A0A8Q3WLC2
A0A8Q3SIK9
A0A8Q3SIR8
ENST00000696598.1
ENST00000696319.1
ENST00000696308.1
ENST00000696362.1
ENST00000696499.1
ENST00000696511.1
ENST00000696361.1
ENST00000696373.1
ENST00000481670.3
ENST00000696379.1
A0A8Q3WMD8
ENST00000696435.1
ENST00000696418.1
ENST00000696476.1
ENST00000696467.1
A0A8Q3WMF8
A0A8Q3SIL3
ENST00000696495.1
ENST00000696306.1
ENST00000696508.1
ENST00000403676.6
A0A087X0C0
ENST00000696454.1
A0A8Q3WMF1
ENST00000696596.1
ENST00000696438.1
ENST00000427708.7
A0A8Q3WLB8
ENST00000696314.1
A0A8Q3SIH3
ENST00000696595.1
A0A8Q3WLA4
ENST00000696417.1
ENST00000696565.1
A0A8Q3WMD3
Q9NW38
A0A8Q3WLD6
ENST00000696459.1
ENST00000696530.1
ENST00000696461.1
ENST00000696543.1
A0A8Q3WLA5
ENST00000696458.1
A0A8Q3SIP2
A0A8Q3SIH1
ENST00000696548.1
ENST00000696324.1
ENST00000402135.8 [Q9NW38-2]
A0A8Q3WLB5
C9J512
B5MC31
ENST00000696403.1
ENST00000696321.1
ENST00000696531.1
A0A8Q3SIS2
ENST00000696551.1
ENST00000417361.2
ENST00000696468.1
ENST00000696433.1
ENST00000696549.1
ENST00000696473.1
ENST00000696624.1
A0A8Q3WLA7
A0A8Q3SIM1
B5MCZ6
ENST00000696410.1
ENST00000696400.1
ENST00000696510.1
ENST00000696398.1
ENST00000696478.1
A0A8Q3WLW1
ENST00000696318.1
A0A8Q3SIX5
A0A8Q3WL94
ENST00000696457.1
A0A8Q3WMH1
ENST00000696564.1
A0A8Q3WM99
ENST00000696635.1
A0A8Q3SIS7
A0A8Q3WLF1
ENST00000696625.1
ENST00000696409.1
ENST00000696316.1
A0A8Q3WL63
A0A8Q3WL68
ENST00000696347.1
ENST00000696305.1
ENST00000696547.1
ENST00000696621.1
ENST00000696378.1
ENST00000696597.1
A0A8Q3SIP3
A0A8Q3SIQ9
A0A8Q3WLE2
A0A8Q3WL86
ENST00000696544.1
A0A8Q3SIK5
A0A8Q3SIQ5
A0A8Q3SIR9
B4DN24
ENST00000696509.1
ENST00000696434.1