I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 7% | |
| transit amplifying cell | 3 studies | 47% ± 24% | |
| natural killer cell | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 22% ± 7% | |
| transit amplifying cell | 3 studies | 47% ± 24% | |
| natural killer cell | 3 studies | 20% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 23% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 99% | 775.45 | 1425 / 1445 | 100% | 18.27 | 183 / 183 |
| uterus | 100% | 468.59 | 170 / 170 | 98% | 18.25 | 449 / 459 |
| intestine | 100% | 691.99 | 965 / 966 | 96% | 13.05 | 506 / 527 |
| bladder | 100% | 449.14 | 21 / 21 | 96% | 12.24 | 483 / 504 |
| skin | 100% | 1610.81 | 1809 / 1809 | 96% | 15.41 | 451 / 472 |
| breast | 100% | 586.74 | 458 / 459 | 96% | 12.93 | 1070 / 1118 |
| stomach | 99% | 644.30 | 356 / 359 | 95% | 12.11 | 273 / 286 |
| lung | 99% | 668.33 | 573 / 578 | 90% | 12.32 | 1044 / 1155 |
| ovary | 100% | 488.00 | 180 / 180 | 86% | 7.20 | 370 / 430 |
| pancreas | 85% | 221.41 | 278 / 328 | 76% | 5.15 | 136 / 178 |
| brain | 83% | 224.45 | 2182 / 2642 | 60% | 5.65 | 425 / 705 |
| prostate | 100% | 549.08 | 244 / 245 | 40% | 1.93 | 203 / 502 |
| thymus | 94% | 257.95 | 613 / 653 | 30% | 2.94 | 179 / 605 |
| adrenal gland | 100% | 458.20 | 257 / 258 | 21% | 1.29 | 49 / 230 |
| kidney | 71% | 235.33 | 63 / 89 | 37% | 1.83 | 333 / 901 |
| adipose | 100% | 584.84 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1089.87 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 21.75 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.65 | 1 / 1 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 15.57 | 27 / 29 |
| blood vessel | 93% | 299.46 | 1236 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 85% | 2068.13 | 791 / 929 | 0% | 0 | 0 / 0 |
| liver | 45% | 135.01 | 102 / 226 | 36% | 2.21 | 146 / 406 |
| heart | 63% | 149.01 | 545 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 36% | 1.54 | 29 / 80 |
| muscle | 30% | 69.82 | 243 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031398 | Biological process | positive regulation of protein ubiquitination |
| GO_0036297 | Biological process | interstrand cross-link repair |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_1990391 | Cellular component | DNA repair complex |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0070182 | Molecular function | DNA polymerase binding |
| Gene name | FANCI |
| Protein name | FA complementation group I Fanconi anemia, complementation group I Fanconi anemia group I protein (Protein FACI) |
| Synonyms | KIAA1794 |
| Description | FUNCTION: Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage. . |
| Accessions | A0A6Q8PGF4 ENST00000696719.1 [Q9NVI1-3] H3BMG4 B7ZMF2 ENST00000696718.1 ENST00000564920.5 ENST00000674831.1 ENST00000567996.5 [Q9NVI1-4] ENST00000563250.5 F8W7R3 ENST00000561894.1 H3BN35 ENST00000300027.12 [Q9NVI1-1] H3BP78 ENST00000696717.1 ENST00000570225.5 A0A6Q8PH09 ENST00000676003.1 Q9NVI1 ENST00000310775.12 [Q9NVI1-3] ENST00000447611.6 H3BT54 H3BQE2 A0A8Q3SIZ6 ENST00000565255.5 H3BS60 ENST00000567891.5 A0A8Q3SIW9 |
