Name | Number of supported studies | Average coverage | |
---|---|---|---|
non-classical monocyte | 7 studies | 35% ± 23% | |
endothelial cell | 7 studies | 25% ± 8% | |
smooth muscle cell | 6 studies | 21% ± 4% | |
natural killer cell | 5 studies | 21% ± 7% | |
CD8-positive, alpha-beta T cell | 4 studies | 25% ± 8% | |
conventional dendritic cell | 4 studies | 32% ± 23% | |
fibroblast | 4 studies | 21% ± 3% | |
pericyte | 4 studies | 22% ± 5% | |
T cell | 3 studies | 22% ± 4% | |
B cell | 3 studies | 18% ± 0% | |
CD4-positive, alpha-beta T cell | 3 studies | 26% ± 6% | |
mature NK T cell | 3 studies | 22% ± 6% | |
abnormal cell | 3 studies | 19% ± 3% | |
plasma cell | 3 studies | 30% ± 14% | |
epithelial cell | 3 studies | 31% ± 7% | |
ciliated cell | 3 studies | 21% ± 4% | |
regulatory T cell | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 36% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 486.68 | 1445 / 1445 | 100% | 10.17 | 183 / 183 |
ovary | 100% | 383.98 | 180 / 180 | 100% | 20.18 | 430 / 430 |
uterus | 100% | 453.00 | 170 / 170 | 100% | 10.81 | 459 / 459 |
brain | 100% | 431.64 | 2638 / 2642 | 100% | 8.27 | 704 / 705 |
prostate | 100% | 526.97 | 245 / 245 | 100% | 12.03 | 500 / 502 |
stomach | 100% | 334.55 | 359 / 359 | 99% | 9.31 | 284 / 286 |
bladder | 100% | 538.19 | 21 / 21 | 99% | 12.00 | 500 / 504 |
lung | 100% | 381.64 | 577 / 578 | 99% | 8.14 | 1147 / 1155 |
intestine | 100% | 488.95 | 966 / 966 | 99% | 8.86 | 522 / 527 |
pancreas | 100% | 370.61 | 328 / 328 | 99% | 9.88 | 176 / 178 |
breast | 100% | 327.98 | 459 / 459 | 99% | 9.76 | 1105 / 1118 |
skin | 100% | 335.61 | 1808 / 1809 | 99% | 7.65 | 465 / 472 |
thymus | 100% | 276.03 | 652 / 653 | 96% | 8.18 | 582 / 605 |
kidney | 100% | 271.69 | 89 / 89 | 94% | 6.53 | 847 / 901 |
adrenal gland | 100% | 297.85 | 258 / 258 | 94% | 7.40 | 216 / 230 |
liver | 98% | 182.18 | 221 / 226 | 92% | 4.87 | 375 / 406 |
adipose | 100% | 356.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 8.38 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.45 | 29 / 29 |
muscle | 100% | 638.35 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 469.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 7.62 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 59.46 | 1 / 1 |
blood vessel | 100% | 571.18 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 284.36 | 859 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 371.66 | 905 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030010 | Biological process | establishment of cell polarity |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0060392 | Biological process | negative regulation of SMAD protein signal transduction |
GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
GO_0030027 | Cellular component | lamellipodium |
GO_0005737 | Cellular component | cytoplasm |
GO_0001222 | Molecular function | transcription corepressor binding |
Gene name | FAM89B |
Protein name | Leucine repeat adapter protein 25 |
Synonyms | Lrap25 |
Description | FUNCTION: Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. . |
Accessions | ENST00000449319.2 [Q8N5H3-4] ENST00000316409.2 [Q8N5H3-1] Q8N5H3 ENST00000530349.2 [Q8N5H3-3] |