Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 26% ± 7% | |
transit amplifying cell | 3 studies | 30% ± 13% |
Insufficient scRNA-seq data for expression of FAM83B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 38% | 737.35 | 556 / 1445 | 99% | 31.56 | 181 / 183 |
intestine | 37% | 252.21 | 361 / 966 | 90% | 8.62 | 473 / 527 |
bladder | 33% | 232.76 | 7 / 21 | 84% | 8.82 | 423 / 504 |
thymus | 54% | 185.79 | 355 / 653 | 52% | 2.49 | 316 / 605 |
stomach | 13% | 45.92 | 47 / 359 | 90% | 8.82 | 256 / 286 |
tonsil | 0% | 0 | 0 / 0 | 89% | 18.79 | 40 / 45 |
skin | 72% | 2460.30 | 1303 / 1809 | 7% | 0.49 | 33 / 472 |
pancreas | 3% | 9.25 | 10 / 328 | 75% | 5.04 | 134 / 178 |
uterus | 2% | 21.57 | 3 / 170 | 71% | 10.67 | 324 / 459 |
breast | 10% | 34.59 | 48 / 459 | 54% | 4.76 | 608 / 1118 |
lung | 0% | 0 | 0 / 578 | 62% | 10.44 | 720 / 1155 |
prostate | 42% | 154.04 | 103 / 245 | 13% | 0.41 | 66 / 502 |
kidney | 21% | 77.10 | 19 / 89 | 11% | 0.68 | 98 / 901 |
ovary | 0% | 0 | 0 / 180 | 13% | 0.41 | 54 / 430 |
heart | 10% | 30.97 | 83 / 861 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 8% | 0.55 | 32 / 406 |
muscle | 1% | 4.13 | 12 / 803 | 0% | 0 | 0 / 0 |
adipose | 0% | 3.76 | 6 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 1.84 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
GO_0008283 | Biological process | cell population proliferation |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0036313 | Molecular function | phosphatidylinositol 3-kinase catalytic subunit binding |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0036312 | Molecular function | phosphatidylinositol 3-kinase regulatory subunit binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005515 | Molecular function | protein binding |
GO_0004630 | Molecular function | phospholipase D activity |
Gene name | FAM83B |
Protein name | Protein FAM83B |
Synonyms | C6orf143 |
Description | FUNCTION: Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades. . |
Accessions | Q5T0W9 ENST00000306858.8 |