FAM83B report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FAM83B at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0045742Biological processpositive regulation of epidermal growth factor receptor signaling pathway
GO_0008283Biological processcell population proliferation
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0036313Molecular functionphosphatidylinositol 3-kinase catalytic subunit binding
GO_0005154Molecular functionepidermal growth factor receptor binding
GO_0036312Molecular functionphosphatidylinositol 3-kinase regulatory subunit binding
GO_0019901Molecular functionprotein kinase binding
GO_0005515Molecular functionprotein binding
GO_0004630Molecular functionphospholipase D activity

IV. Literature review

[source]
Gene nameFAM83B
Protein nameProtein FAM83B
SynonymsC6orf143
DescriptionFUNCTION: Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades. .

AccessionsQ5T0W9
ENST00000306858.8