FAAH2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0019369Biological processarachidonic acid metabolic process
GO_0016042Biological processlipid catabolic process
GO_0005811Cellular componentlipid droplet
GO_0016020Cellular componentmembrane
GO_0017064Molecular functionfatty acid amide hydrolase activity

IV. Literature review

[source]
Gene nameFAAH2
Protein nameFatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide amidohydrolase 2) (Oleamide hydrolase 2)
SynonymsAMDD
DescriptionFUNCTION: Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules . Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. .

AccessionsENST00000374900.5
Q6GMR7