Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 28 studies | 46% ± 24% | |
| classical monocyte | 17 studies | 22% ± 5% | |
| platelet | 11 studies | 60% ± 19% | |
| conventional dendritic cell | 9 studies | 22% ± 5% | |
| myeloid cell | 9 studies | 47% ± 20% | |
| monocyte | 8 studies | 28% ± 15% | |
| dendritic cell | 7 studies | 33% ± 11% | |
| megakaryocyte | 4 studies | 43% ± 21% | |
| mononuclear phagocyte | 4 studies | 29% ± 5% |
Insufficient scRNA-seq data for expression of F13A1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 96% | 8342.54 | 439 / 459 | 87% | 45.30 | 973 / 1118 |
| lung | 90% | 5477.56 | 523 / 578 | 77% | 35.00 | 887 / 1155 |
| bladder | 100% | 5905.67 | 21 / 21 | 50% | 27.12 | 253 / 504 |
| thymus | 71% | 3427.47 | 465 / 653 | 75% | 17.29 | 452 / 605 |
| adrenal gland | 87% | 6844.53 | 225 / 258 | 57% | 27.64 | 131 / 230 |
| skin | 67% | 2601.19 | 1206 / 1809 | 64% | 22.01 | 301 / 472 |
| kidney | 65% | 3402.16 | 58 / 89 | 65% | 36.49 | 584 / 901 |
| intestine | 92% | 5019.66 | 885 / 966 | 38% | 12.06 | 202 / 527 |
| stomach | 73% | 3319.57 | 261 / 359 | 47% | 13.23 | 133 / 286 |
| ovary | 47% | 1864.03 | 84 / 180 | 65% | 19.59 | 279 / 430 |
| pancreas | 21% | 381.85 | 70 / 328 | 86% | 45.66 | 153 / 178 |
| esophagus | 70% | 4303.41 | 1009 / 1445 | 33% | 7.98 | 61 / 183 |
| uterus | 55% | 2057.21 | 93 / 170 | 47% | 13.34 | 216 / 459 |
| adipose | 99% | 17470.33 | 1189 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 88% | 4395.31 | 815 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 85% | 5804.95 | 1132 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 43% | 1401.21 | 105 / 245 | 36% | 6.17 | 183 / 502 |
| spleen | 65% | 1416.48 | 156 / 241 | 0% | 0 | 0 / 0 |
| heart | 63% | 2528.78 | 543 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 10.16 | 24 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 52% | 14.53 | 15 / 29 |
| brain | 6% | 129.27 | 162 / 2642 | 42% | 38.11 | 293 / 705 |
| eye | 0% | 0 | 0 / 0 | 38% | 5.76 | 30 / 80 |
| muscle | 34% | 864.27 | 273 / 803 | 0% | 0 | 0 / 0 |
| liver | 4% | 92.65 | 10 / 226 | 26% | 6.55 | 105 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0018149 | Biological process | peptide cross-linking |
| GO_0007596 | Biological process | blood coagulation |
| GO_0072378 | Biological process | blood coagulation, fibrin clot formation |
| GO_0005615 | Cellular component | extracellular space |
| GO_0072562 | Cellular component | blood microparticle |
| GO_0031093 | Cellular component | platelet alpha granule lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_1990234 | Cellular component | transferase complex |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003810 | Molecular function | protein-glutamine gamma-glutamyltransferase activity |
| Gene name | F13A1 |
| Protein name | Coagulation factor XIII A chain (Coagulation factor XIIIa) (EC 2.3.2.13) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain) Coagulation factor XIII A chain Coagulation factor XIII Blood coagulation factor XIII a subunit |
| Synonyms | F13A |
| Description | FUNCTION: Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. . |
| Accessions | A6PVK5 A0A2H0 ENST00000451619.1 ENST00000445223.1 Q9NZ69 H0Y4W5 H0Y796 ENST00000414279.5 Q9NQP5 ENST00000431222.6 P00488 ENST00000264870.8 |