Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 23% ± 6% | |
epithelial cell | 6 studies | 30% ± 13% | |
macrophage | 6 studies | 21% ± 4% | |
natural killer cell | 5 studies | 20% ± 4% | |
microglial cell | 5 studies | 20% ± 4% | |
GABAergic neuron | 5 studies | 39% ± 19% | |
oligodendrocyte | 5 studies | 25% ± 4% | |
B cell | 4 studies | 18% ± 2% | |
T cell | 4 studies | 16% ± 1% | |
CD8-positive, alpha-beta T cell | 4 studies | 20% ± 3% | |
basal cell | 4 studies | 23% ± 7% | |
CD8-positive, alpha-beta memory T cell | 4 studies | 16% ± 1% | |
astrocyte | 4 studies | 28% ± 6% | |
glutamatergic neuron | 4 studies | 51% ± 19% | |
oligodendrocyte precursor cell | 4 studies | 25% ± 8% | |
fibroblast | 4 studies | 19% ± 6% | |
endothelial cell of lymphatic vessel | 4 studies | 16% ± 2% | |
interneuron | 4 studies | 36% ± 23% | |
naive B cell | 3 studies | 17% ± 2% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 20% ± 2% | |
CD4-positive, alpha-beta T cell | 3 studies | 21% ± 5% | |
ciliated cell | 3 studies | 23% ± 4% | |
lymphocyte | 3 studies | 23% ± 1% | |
myeloid cell | 3 studies | 21% ± 3% | |
monocyte | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1107.18 | 459 / 459 | 100% | 21.39 | 1117 / 1118 |
prostate | 100% | 1183.29 | 245 / 245 | 100% | 16.74 | 501 / 502 |
lung | 100% | 899.09 | 576 / 578 | 100% | 17.62 | 1155 / 1155 |
thymus | 100% | 1268.20 | 653 / 653 | 100% | 17.28 | 602 / 605 |
esophagus | 100% | 1080.76 | 1445 / 1445 | 99% | 21.29 | 182 / 183 |
brain | 100% | 725.81 | 2631 / 2642 | 100% | 13.29 | 704 / 705 |
uterus | 100% | 1116.54 | 170 / 170 | 99% | 16.79 | 454 / 459 |
ovary | 100% | 1130.88 | 180 / 180 | 99% | 11.35 | 425 / 430 |
pancreas | 100% | 600.36 | 327 / 328 | 99% | 16.76 | 176 / 178 |
bladder | 100% | 1142.52 | 21 / 21 | 98% | 14.17 | 496 / 504 |
stomach | 100% | 840.31 | 359 / 359 | 97% | 13.01 | 277 / 286 |
intestine | 100% | 1118.36 | 966 / 966 | 97% | 12.86 | 510 / 527 |
kidney | 100% | 875.26 | 89 / 89 | 97% | 11.19 | 871 / 901 |
skin | 100% | 1191.84 | 1809 / 1809 | 96% | 18.14 | 452 / 472 |
liver | 100% | 688.88 | 226 / 226 | 95% | 9.14 | 386 / 406 |
adrenal gland | 100% | 812.60 | 258 / 258 | 93% | 9.39 | 215 / 230 |
blood vessel | 100% | 1147.14 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 19.17 | 29 / 29 |
spleen | 100% | 1144.76 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 16.10 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.33 | 1 / 1 |
adipose | 100% | 1003.88 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 1139.89 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 565.60 | 833 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 828.03 | 791 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 69% | 7.28 | 55 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007062 | Biological process | sister chromatid cohesion |
GO_0034421 | Biological process | post-translational protein acetylation |
GO_0006275 | Biological process | regulation of DNA replication |
GO_0018394 | Biological process | peptidyl-lysine acetylation |
GO_0007064 | Biological process | mitotic sister chromatid cohesion |
GO_0005694 | Cellular component | chromosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0016407 | Molecular function | acetyltransferase activity |
GO_0008080 | Molecular function | N-acetyltransferase activity |
GO_0061733 | Molecular function | peptide-lysine-N-acetyltransferase activity |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | ESCO1 |
Protein name | Establishment of sister chromatid cohesion N-acetyltransferase 1 N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) |
Synonyms | EFO1 KIAA1911 |
Description | FUNCTION: Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3 . . |
Accessions | ENST00000383276.1 [Q5FWF5-2] ENST00000269214.10 [Q5FWF5-1] Q5FWF5 A0A0C4DH04 ENST00000622333.1 |