ESCO1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007062Biological processsister chromatid cohesion
GO_0034421Biological processpost-translational protein acetylation
GO_0006275Biological processregulation of DNA replication
GO_0018394Biological processpeptidyl-lysine acetylation
GO_0007064Biological processmitotic sister chromatid cohesion
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0016407Molecular functionacetyltransferase activity
GO_0008080Molecular functionN-acetyltransferase activity
GO_0061733Molecular functionpeptide-lysine-N-acetyltransferase activity
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameESCO1
Protein nameEstablishment of sister chromatid cohesion N-acetyltransferase 1
N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1)
SynonymsEFO1
KIAA1911
DescriptionFUNCTION: Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3 . .

AccessionsENST00000383276.1 [Q5FWF5-2]
ENST00000269214.10 [Q5FWF5-1]
Q5FWF5
A0A0C4DH04
ENST00000622333.1