Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 12 studies | 43% ± 13% | |
ciliated cell | 12 studies | 27% ± 8% | |
epithelial cell | 12 studies | 35% ± 16% | |
basal cell | 6 studies | 32% ± 13% | |
enterocyte | 6 studies | 25% ± 4% | |
epithelial cell of proximal tubule | 5 studies | 25% ± 4% | |
squamous epithelial cell | 4 studies | 61% ± 17% | |
club cell | 4 studies | 27% ± 6% | |
goblet cell | 4 studies | 22% ± 6% | |
respiratory goblet cell | 3 studies | 23% ± 5% | |
secretory cell | 3 studies | 31% ± 7% | |
type II pneumocyte | 3 studies | 22% ± 9% | |
hepatocyte | 3 studies | 34% ± 19% | |
brush cell | 3 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 6176.18 | 327 / 328 | 99% | 79.61 | 177 / 178 |
kidney | 100% | 20721.56 | 89 / 89 | 98% | 112.53 | 885 / 901 |
liver | 100% | 12741.13 | 226 / 226 | 97% | 62.59 | 395 / 406 |
prostate | 97% | 8808.30 | 237 / 245 | 99% | 50.41 | 497 / 502 |
thymus | 100% | 19569.55 | 652 / 653 | 94% | 56.23 | 571 / 605 |
lung | 97% | 6760.62 | 563 / 578 | 96% | 56.12 | 1107 / 1155 |
ovary | 84% | 2423.81 | 151 / 180 | 97% | 56.02 | 419 / 430 |
uterus | 88% | 3415.14 | 150 / 170 | 92% | 71.85 | 421 / 459 |
stomach | 83% | 6164.20 | 299 / 359 | 96% | 62.26 | 274 / 286 |
esophagus | 73% | 13661.43 | 1052 / 1445 | 97% | 66.78 | 178 / 183 |
breast | 71% | 6146.27 | 326 / 459 | 95% | 48.37 | 1064 / 1118 |
intestine | 66% | 6710.09 | 642 / 966 | 98% | 68.69 | 516 / 527 |
bladder | 67% | 3189.90 | 14 / 21 | 96% | 74.63 | 483 / 504 |
skin | 89% | 9527.93 | 1615 / 1809 | 28% | 10.90 | 130 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 171.61 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 64.63 | 44 / 45 |
eye | 0% | 0 | 0 / 0 | 98% | 57.60 | 78 / 80 |
adrenal gland | 66% | 2013.03 | 171 / 258 | 13% | 4.00 | 29 / 230 |
blood vessel | 62% | 1895.17 | 826 / 1335 | 0% | 0 | 0 / 0 |
adipose | 40% | 1060.51 | 481 / 1204 | 0% | 0 | 0 / 0 |
brain | 28% | 1412.93 | 730 / 2642 | 12% | 2.25 | 82 / 705 |
lymph node | 0% | 0 | 0 / 0 | 24% | 4.85 | 7 / 29 |
heart | 4% | 79.34 | 31 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 3% | 59.53 | 27 / 929 | 0% | 0 | 0 / 0 |
spleen | 1% | 22.57 | 2 / 241 | 0% | 0 | 0 / 0 |
muscle | 1% | 15.19 | 6 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0007605 | Biological process | sensory perception of sound |
GO_1900029 | Biological process | positive regulation of ruffle assembly |
GO_0035023 | Biological process | regulation of Rho protein signal transduction |
GO_0032587 | Cellular component | ruffle membrane |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0031982 | Cellular component | vesicle |
GO_0032426 | Cellular component | stereocilium tip |
GO_0005886 | Cellular component | plasma membrane |
GO_0032421 | Cellular component | stereocilium bundle |
GO_0045296 | Molecular function | cadherin binding |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | EPS8L2 |
Protein name | Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2) EPS8 like 2 |
Synonyms | EPS8R2 PP13181 |
Description | FUNCTION: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity). . |
Accessions | ENST00000528770.5 H0YF37 ENST00000530636.5 [Q9H6S3-1] ENST00000533256.5 [Q9H6S3-1] A0A3B3ISQ4 ENST00000527199.5 ENST00000526909.5 ENST00000650127.1 ENST00000524763.5 ENST00000534755.5 ENST00000526198.5 [Q9H6S3-3] H0YD62 E9PM34 ENST00000614442.4 [Q9H6S3-3] E9PLN2 E9PN68 ENST00000531348.5 E9PNT0 E9PNY4 Q9H6S3 ENST00000533500.5 E9PLH1 ENST00000530452.6 ENST00000318562.13 [Q9H6S3-1] |