Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 27 studies | 38% ± 16% | |
| endothelial cell | 25 studies | 30% ± 12% | |
| pericyte | 23 studies | 27% ± 9% | |
| endothelial cell of lymphatic vessel | 19 studies | 38% ± 16% | |
| ciliated cell | 17 studies | 51% ± 17% | |
| basal cell | 15 studies | 37% ± 19% | |
| capillary endothelial cell | 11 studies | 25% ± 5% | |
| astrocyte | 11 studies | 31% ± 13% | |
| connective tissue cell | 11 studies | 29% ± 6% | |
| epithelial cell | 10 studies | 34% ± 14% | |
| type II pneumocyte | 8 studies | 42% ± 15% | |
| smooth muscle cell | 8 studies | 29% ± 12% | |
| vein endothelial cell | 8 studies | 23% ± 6% | |
| club cell | 7 studies | 45% ± 13% | |
| endothelial cell of artery | 7 studies | 24% ± 4% | |
| endothelial cell of vascular tree | 7 studies | 27% ± 7% | |
| myofibroblast cell | 7 studies | 29% ± 10% | |
| adipocyte | 7 studies | 27% ± 14% | |
| respiratory goblet cell | 6 studies | 41% ± 10% | |
| secretory cell | 6 studies | 48% ± 18% | |
| hepatocyte | 6 studies | 47% ± 26% | |
| macrophage | 5 studies | 20% ± 3% | |
| adventitial cell | 4 studies | 41% ± 8% | |
| abnormal cell | 4 studies | 27% ± 10% | |
| duct epithelial cell | 3 studies | 32% ± 21% | |
| hillock cell | 3 studies | 30% ± 16% | |
| epithelial cell of proximal tubule | 3 studies | 18% ± 2% | |
| serous secreting cell | 3 studies | 29% ± 16% | |
| Mueller cell | 3 studies | 29% ± 5% | |
| oligodendrocyte | 3 studies | 24% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 9027.79 | 245 / 245 | 99% | 245.93 | 499 / 502 |
| ovary | 100% | 23615.32 | 180 / 180 | 99% | 299.58 | 427 / 430 |
| liver | 100% | 46574.27 | 226 / 226 | 99% | 2650.39 | 403 / 406 |
| brain | 97% | 6451.92 | 2575 / 2642 | 99% | 183.87 | 701 / 705 |
| breast | 100% | 12528.30 | 459 / 459 | 96% | 251.24 | 1073 / 1118 |
| thymus | 100% | 14135.22 | 653 / 653 | 96% | 177.31 | 579 / 605 |
| pancreas | 100% | 9926.91 | 328 / 328 | 96% | 129.30 | 170 / 178 |
| lung | 100% | 8345.41 | 576 / 578 | 92% | 366.42 | 1057 / 1155 |
| uterus | 100% | 10667.41 | 170 / 170 | 87% | 219.27 | 401 / 459 |
| kidney | 100% | 6042.83 | 89 / 89 | 87% | 152.38 | 786 / 901 |
| esophagus | 100% | 8581.82 | 1445 / 1445 | 85% | 190.39 | 155 / 183 |
| skin | 96% | 4464.21 | 1741 / 1809 | 76% | 185.75 | 361 / 472 |
| bladder | 100% | 10059.95 | 21 / 21 | 71% | 143.77 | 360 / 504 |
| stomach | 99% | 6104.78 | 357 / 359 | 63% | 78.85 | 181 / 286 |
| intestine | 99% | 5538.41 | 958 / 966 | 57% | 62.62 | 300 / 527 |
| adrenal gland | 100% | 85895.34 | 258 / 258 | 55% | 557.38 | 126 / 230 |
| adipose | 100% | 16665.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 67.93 | 1 / 1 |
| blood vessel | 98% | 5937.37 | 1309 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 97% | 6040.81 | 778 / 803 | 0% | 0 | 0 / 0 |
| spleen | 94% | 3743.49 | 226 / 241 | 0% | 0 | 0 / 0 |
| heart | 93% | 4228.93 | 802 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 167.85 | 71 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 129.56 | 37 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 24% | 20.39 | 7 / 29 |
| peripheral blood | 1% | 16.14 | 6 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0014070 | Biological process | response to organic cyclic compound |
| GO_0097176 | Biological process | epoxide metabolic process |
| GO_0009636 | Biological process | response to toxic substance |
| GO_0006805 | Biological process | xenobiotic metabolic process |
| GO_0019369 | Biological process | arachidonic acid metabolic process |
| GO_0009056 | Biological process | catabolic process |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0033961 | Molecular function | cis-stilbene-oxide hydrolase activity |
| GO_0004301 | Molecular function | epoxide hydrolase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008142 | Molecular function | oxysterol binding |
| Gene name | EPHX1 |
| Protein name | Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) Epoxide hydrolase (EC 3.3.2.9) Epoxide hydrolase 1 microsomal isoform 2 Epoxide hydrolase 1 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) |
| Synonyms | EPHX EPOX hCG_2039431 |
| Description | FUNCTION: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids . Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol . Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity). . FUNCTION: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. . |
| Accessions | ENST00000614058.4 ENST00000366837.5 ENST00000448202.5 A0A0S2Z3T1 Q6FGZ3 P07099 ENST00000272167.10 R4SBI6 B1AQP8 |