Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 26% ± 11% | |
GABAergic neuron | 7 studies | 34% ± 19% | |
macrophage | 6 studies | 27% ± 7% | |
microglial cell | 6 studies | 24% ± 7% | |
oligodendrocyte | 6 studies | 26% ± 8% | |
interneuron | 5 studies | 36% ± 22% | |
oligodendrocyte precursor cell | 5 studies | 26% ± 8% | |
astrocyte | 5 studies | 30% ± 11% | |
glutamatergic neuron | 5 studies | 47% ± 24% | |
epithelial cell | 4 studies | 29% ± 14% | |
natural killer cell | 4 studies | 17% ± 1% | |
fibroblast | 4 studies | 20% ± 6% | |
neuron | 3 studies | 27% ± 9% | |
endothelial cell of lymphatic vessel | 3 studies | 20% ± 2% | |
type I pneumocyte | 3 studies | 19% ± 4% | |
adipocyte | 3 studies | 18% ± 2% | |
mast cell | 3 studies | 18% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 7 studies | 37% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2869.70 | 1445 / 1445 | 100% | 11.42 | 183 / 183 |
skin | 100% | 5414.40 | 1809 / 1809 | 100% | 17.62 | 471 / 472 |
thymus | 100% | 4731.19 | 653 / 653 | 100% | 14.01 | 602 / 605 |
breast | 100% | 3213.09 | 459 / 459 | 99% | 14.12 | 1112 / 1118 |
lung | 100% | 4143.18 | 578 / 578 | 99% | 9.69 | 1147 / 1155 |
prostate | 100% | 2756.45 | 245 / 245 | 99% | 8.40 | 498 / 502 |
kidney | 100% | 2289.06 | 89 / 89 | 98% | 9.66 | 884 / 901 |
pancreas | 100% | 1616.45 | 327 / 328 | 98% | 7.26 | 174 / 178 |
stomach | 100% | 2080.19 | 358 / 359 | 98% | 7.62 | 279 / 286 |
bladder | 100% | 2550.52 | 21 / 21 | 97% | 7.42 | 490 / 504 |
uterus | 100% | 3443.88 | 170 / 170 | 97% | 8.39 | 446 / 459 |
brain | 97% | 1965.63 | 2568 / 2642 | 100% | 9.42 | 704 / 705 |
intestine | 100% | 2618.19 | 966 / 966 | 97% | 6.39 | 511 / 527 |
ovary | 100% | 3969.43 | 180 / 180 | 96% | 6.92 | 414 / 430 |
adrenal gland | 100% | 3002.10 | 258 / 258 | 95% | 7.59 | 218 / 230 |
liver | 100% | 1312.92 | 226 / 226 | 83% | 4.13 | 337 / 406 |
adipose | 100% | 2994.43 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2698.04 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2507.25 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3906.53 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 10.39 | 45 / 45 |
peripheral blood | 98% | 2580.02 | 906 / 929 | 0% | 0 | 0 / 0 |
heart | 97% | 2356.59 | 834 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 10.43 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 94% | 9.08 | 75 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0034162 | Biological process | toll-like receptor 9 signaling pathway |
GO_0097352 | Biological process | autophagosome maturation |
GO_0008333 | Biological process | endosome to lysosome transport |
GO_0032456 | Biological process | endocytic recycling |
GO_1990786 | Biological process | cellular response to dsDNA |
GO_0006862 | Biological process | nucleotide transport |
GO_0005764 | Cellular component | lysosome |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | EPG5 |
Protein name | Ectopic P-granules 5 autophagy tethering factor Ectopic P granules protein 5 homolog |
Synonyms | KIAA1632 |
Description | FUNCTION: Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located . . |
Accessions | A0A8Q3SIJ4 ENST00000590884.6 ENST00000587884.2 Q9HCE0 A0A8Q3SIJ2 ENST00000696484.1 ENST00000696489.1 K7EPN4 ENST00000587262.1 A0A8Q3WLI3 ENST00000696482.1 ENST00000696483.1 ENST00000696490.1 K7EM87 K7ENK5 ENST00000282041.11 [Q9HCE0-1] A0A8Q3SJD2 ENST00000696485.1 ENST00000592272.6 A0A8Q3SIP5 A0A8Q3SIU6 |