Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 34% ± 10% | |
| fibroblast | 5 studies | 22% ± 9% | |
| natural killer cell | 5 studies | 21% ± 4% | |
| CD16-negative, CD56-bright natural killer cell, human | 4 studies | 19% ± 4% | |
| CD4-positive, alpha-beta T cell | 4 studies | 18% ± 4% | |
| macrophage | 4 studies | 21% ± 3% | |
| CD8-positive, alpha-beta T cell | 4 studies | 19% ± 3% | |
| conventional dendritic cell | 3 studies | 24% ± 5% | |
| hematopoietic precursor cell | 3 studies | 26% ± 8% | |
| non-classical monocyte | 3 studies | 17% ± 1% | |
| connective tissue cell | 3 studies | 22% ± 4% | |
| basal cell | 3 studies | 31% ± 11% | |
| precursor B cell | 3 studies | 20% ± 3% | |
| endothelial cell | 3 studies | 23% ± 8% | |
| ciliated cell | 3 studies | 26% ± 6% | |
| B cell | 3 studies | 19% ± 5% | |
| dendritic cell | 3 studies | 31% ± 4% | |
| intestinal crypt stem cell | 3 studies | 18% ± 2% | |
| plasmacytoid dendritic cell | 3 studies | 21% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 4 studies | 23% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1537.00 | 1445 / 1445 | 100% | 29.48 | 183 / 183 |
| intestine | 100% | 1844.46 | 966 / 966 | 100% | 30.41 | 527 / 527 |
| kidney | 100% | 1839.08 | 89 / 89 | 100% | 35.69 | 901 / 901 |
| liver | 100% | 1551.56 | 226 / 226 | 100% | 28.51 | 406 / 406 |
| ovary | 100% | 1729.77 | 180 / 180 | 100% | 39.51 | 430 / 430 |
| prostate | 100% | 2094.01 | 245 / 245 | 100% | 38.05 | 502 / 502 |
| skin | 100% | 1351.62 | 1809 / 1809 | 100% | 45.69 | 472 / 472 |
| stomach | 100% | 1255.03 | 359 / 359 | 100% | 28.32 | 286 / 286 |
| thymus | 100% | 1844.43 | 653 / 653 | 100% | 41.58 | 605 / 605 |
| uterus | 100% | 1855.52 | 170 / 170 | 100% | 38.65 | 459 / 459 |
| brain | 100% | 1765.01 | 2640 / 2642 | 100% | 58.68 | 705 / 705 |
| lung | 100% | 1359.49 | 578 / 578 | 100% | 32.00 | 1154 / 1155 |
| breast | 100% | 1563.22 | 459 / 459 | 100% | 30.89 | 1116 / 1118 |
| bladder | 100% | 1710.10 | 21 / 21 | 100% | 35.16 | 503 / 504 |
| pancreas | 100% | 831.59 | 327 / 328 | 100% | 28.11 | 178 / 178 |
| adrenal gland | 100% | 2339.00 | 258 / 258 | 100% | 31.84 | 229 / 230 |
| adipose | 100% | 1522.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 49.57 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 59.87 | 29 / 29 |
| spleen | 100% | 2010.90 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 36.24 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.31 | 1 / 1 |
| muscle | 100% | 1521.34 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1225.52 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 1628.58 | 859 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 84% | 941.85 | 777 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002098 | Biological process | tRNA wobble uridine modification |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0006400 | Biological process | tRNA modification |
| GO_0006417 | Biological process | regulation of translation |
| GO_0033588 | Cellular component | elongator holoenzyme complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0000049 | Molecular function | tRNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ELP5 |
| Protein name | Elongator acetyltransferase complex subunit 5 Elongator complex protein 5 Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein) |
| Synonyms | MSTP071 HSPC002 DERP6 C17orf81 |
| Description | FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) . The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs . Involved in cell migration (By similarity). . |
| Accessions | ENST00000354429.7 [Q8TE02-5] ENST00000573699.6 ENST00000671829.1 [Q8TE02-1] I3L200 I3L1Q3 ENST00000356683.7 [Q8TE02-2] I3L437 I3L2T0 ENST00000574993.6 [Q8TE02-2] ENST00000570500.6 ENST00000673570.1 [Q8TE02-1] ENST00000396628.7 [Q8TE02-5] ENST00000576496.5 I3L1A8 I3NI50 ENST00000570322.6 ENST00000671820.1 [Q8TE02-1] ENST00000574255.6 [Q8TE02-3] ENST00000573657.6 [Q8TE02-3] ENST00000571146.2 I3L2A9 Q8TE02 ENST00000572104.2 ENST00000574841.2 ENST00000396627.7 [Q8TE02-5] |