EFHC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000281Biological processmitotic cytokinesis
GO_0021795Biological processcerebral cortex cell migration
GO_0051302Biological processregulation of cell division
GO_0007052Biological processmitotic spindle organization
GO_0060285Biological processcilium-dependent cell motility
GO_0005930Cellular componentaxoneme
GO_0072686Cellular componentmitotic spindle
GO_0005879Cellular componentaxonemal microtubule
GO_0005813Cellular componentcentrosome
GO_0043025Cellular componentneuronal cell body
GO_0000922Cellular componentspindle pole
GO_0005509Molecular functioncalcium ion binding
GO_0043014Molecular functionalpha-tubulin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameEFHC1
Protein nameEF-hand domain-containing protein 1 (Myoclonin-1)
EF-hand domain (C-terminal) containing 1, isoform CRA_a (EF-hand domain containing 1)
EF-hand domain containing 1
SynonymshCG_21196
DescriptionFUNCTION: Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization . Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration . May enhance calcium influx through CACNA1E and stimulate programmed cell death . Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating . .

AccessionsENST00000636107.1
A0A1B0GTM7
A0A1C7CYY1
ENST00000637263.1
A0A1B0GVP6
ENST00000636343.1
A0A1B0GTV4
ENST00000637602.1
ENST00000480623.6
ENST00000636398.1
A0A1B0GTD7
A0A1B0GU13
ENST00000637200.1
A0A1B0GTV6
A0A1B0GTH7
ENST00000635984.1
A0A1B0GVZ5
ENST00000636954.1 [Q5JVL4-3]
ENST00000635812.1
A0A1B0GUE4
ENST00000636489.1 [Q5JVL4-3]
A0A1B0GTF7
ENST00000538167.2 [Q5JVL4-3]
ENST00000637353.1
A0A1B0GTW5
ENST00000638075.1
A0A1B0GTB1
A0A1B0GTH2
ENST00000635963.1
ENST00000637089.1
A0A1B0GVR3
ENST00000637315.1
B2CKC5
ENST00000636379.1
ENST00000636702.1
A0A1B0GV27
A0A1B0GVB0
ENST00000636566.1
Q5JVL4
ENST00000637874.1
A0A1B0GWB3
ENST00000635866.1
A0A1B0GUV2
ENST00000635996.1
A0A1B0GUP6
ENST00000635760.1
ENST00000371068.11 [Q5JVL4-1]